[在机体生理性衰老过程中肽δ睡眠对大鼠组织抗氧化状态的校正作用]
[Rat tissues antioxidant status correction by peptide delta sleep during physiological aging of the organism].
作者信息
Bondarenko T I, Kutilin D S, Mikhaleva I I
出版信息
Adv Gerontol. 2014;27(1):98-107.
PMID:25051765
Abstract
It is shown that exogenous delta-sleep inducing peptide increases glutathione antioxidant system level in rat tissues at different stages of ontogenesis, by subcutaneous injection to rats 2-24 months postnatal development in a dose of 100 mg/kg animal body weight by courses of 5 consecutive days per month, and this effect is especially marked in non-renewable postmitotic tissues.
摘要
研究表明，通过每月连续5天、以100毫克/千克动物体重的剂量对出生后2至24个月发育阶段的大鼠进行皮下注射，外源性δ-睡眠诱导肽可提高大鼠组织在个体发育不同阶段的谷胱甘肽抗氧化系统水平，且这种作用在不可再生的有丝分裂后组织中尤为明显。
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