Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK.
Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK; Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK.
Cancer Treat Rev. 2014 Oct;40(9):1106-17. doi: 10.1016/j.ctrv.2014.06.011. Epub 2014 Jul 5.
Head and neck cancer patients treated with radiotherapy and/or chemotherapy agents may develop altered taste acuity. This, together with radiation induced xerostomia and dysphagia, is a major contributory factor to the anorexia and concomitant morbidity often seen in this group of patients. This paper examines the existing literature in order to assess the prevalence of clinician and patient-reported dysgeusia in HNC patients undergoing oncological treatment. We also describe the temporal manifestations of the same and its reported impact on QOL.
接受放疗和/或化疗药物治疗的头颈部癌症患者可能会出现味觉敏感度改变。这与放疗引起的口干和吞咽困难一起,是导致这组患者经常出现厌食和相关发病率的主要因素。本文研究了现有文献,以评估接受肿瘤治疗的头颈部癌症患者中临床医生和患者报告的味觉障碍的患病率。我们还描述了味觉障碍的时间表现及其对生活质量的报告影响。