射频消融与乳腺癌：综述
Radiofrequency ablation and breast cancer: a review.
作者信息
Nguyen Tiffany, Hattery Eleanor, Khatri Vijay P
机构信息
Department of Surgery, Division of Surgical Oncology, University of California, Davis Heath System, Sacramento, CA, USA.
出版信息
Gland Surg. 2014 May;3(2):128-35. doi: 10.3978/j.issn.2227-684X.2014.03.05.
BACKGROUND
Radiofrequency ablation (RFA) use in breast cancer is a developing area of research. There have been a number of published studies over the last decade, which explores the feasibility of minimally invasive techniques in breast cancer treatment. In this review, we will discuss the most recent data on radiofrequency ablation and examine the current methods, outcomes, complications, and limitations of RFA in breast cancer therapy.
METHODS
Pub Med search for English Language articles on RFA in breast cancer.
RESULTS
More than 25 studies were reviewed and we searched for number of tumors, average size, electrode used, if they successfully ablated the tumor, when the tumor was then resected and if the patients experienced any complication from the ablation.
CONCLUSIONS
Radiofrequency ablation is an emerging minimally invasive therapy in small, localized breast cancer. Currently, no clinical trials have been published to directly compare RFA to the current standard of surgical resection. Ultimately, RFA will need clinical trials to evaluate oncologic outcomes involving long interval follow-up to determine survival, local control and disease progression before it becomes a reasonable alternative to surgical resection.
背景
乳腺癌的射频消融（RFA）应用是一个正在发展的研究领域。在过去十年中已有多项发表的研究，探讨了微创技术在乳腺癌治疗中的可行性。在本综述中，我们将讨论关于射频消融的最新数据，并研究乳腺癌治疗中RFA的当前方法、结果、并发症及局限性。
方法
在PubMed上搜索关于乳腺癌射频消融的英文文章。
结果
回顾了超过25项研究，我们查找了肿瘤数量、平均大小、使用的电极、是否成功消融肿瘤、肿瘤何时被切除以及患者是否因消融出现任何并发症。
结论
射频消融是一种针对小的、局限性乳腺癌的新兴微创治疗方法。目前，尚无已发表的临床试验将RFA与当前手术切除的标准进行直接比较。最终，射频消融在成为手术切除的合理替代方案之前，需要进行临床试验以评估涉及长期随访的肿瘤学结果，从而确定生存率、局部控制情况和疾病进展。
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