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布基纳法索瓦加杜古地区HIV感染者的生活质量:一项横断面研究

Quality of life in people living with HIV: a cross-sectional study in Ouagadougou, Burkina Faso.

作者信息

Bakiono Fidèle, Ouédraogo Laurent, Sanou Mahamoudou, Samadoulougou Sékou, Guiguemdé Patrice Wendpouiré Laurent, Kirakoya-Samadoulougou Fati, Robert Annie

机构信息

Pôle Epidémiologie et Biostatistique, Institut de Recherche Expérimentale et Clinique (IREC), Faculté de Santé Publique, Université catholique de Louvain, Clos Chapelle-aux-Champs 30, Brussels, 1200 Belgium.

Unité de Formation et de Recherche en Sciences de la santé, Université de Ouagadougou, Ouagadougou 03, 03 BP 7021 Kragujevac, Burkina Faso ; Institut Régional de Santé Publique de Ouidah, Ouidah, BP 384 Bénin.

出版信息

Springerplus. 2014 Jul 21;3:372. doi: 10.1186/2193-1801-3-372. eCollection 2014.

Abstract

HIV/AIDS is a leading cause of death in most of sub-Saharan countries. HIV/AIDS impact on the quality of life of persons living with HIV in Burkina Faso hasn't been well documented. The aim of the study was to assess the quality of life in persons living with HIV and its associated factors. A cross-sectional study was conducted in Ouagadougou. 424 persons living with HIV were included in the study according to their status with regard to Highly Active Anti Retroviral Treatment: 115 were not yet under treatment, 21 started the treatment within the three months preceding the enrolment and 288 were under treatment for at least 12 months. The quality of life was assessed through the WHOQOL HIV-BREF. Statistical comparisons were made using Mann Whitney U test, Kruskal-Wallis H test, Pearson's khi2 or Fisher's exact test. Correlations were appreciated using Spearman's rho. Logistic regression was used to examine associations between the quality of life scores and sociodemographic or clinical variables. The mean global score of quality of life in all patients was 82.4. Better scores were recorded in the spiritual domain and worst scores in the environmental domain. Men had a higher global score than women (p < 0.001). Illiteracy was significantly associated with a lower quality of life (p = 0.001). Patients having support for medical treatment had a significantly better quality of life (p < 0.01). In multivariate analysis, being a man, having a support for medical care, getting older and self-perceived as healthy, were associated with a global score of quality of life higher than 77, that corresponds to the mid-range of the score in our data. These findings suggest the importance of the socio-psychological support and of a good environment in order to improve the quality of life of people living with HIV, especially in women, in younger and in those having no support for medical care. In the environmental domain, actions of HIV services providers should focus on better accessibility to social and health care, promotion of income-generating activities especially for women and youth living with HIV.

摘要

在撒哈拉以南的大多数国家,艾滋病毒/艾滋病是主要死因之一。在布基纳法索,艾滋病毒/艾滋病对艾滋病毒感染者生活质量的影响尚未得到充分记录。本研究的目的是评估艾滋病毒感染者的生活质量及其相关因素。在瓦加杜古进行了一项横断面研究。根据其接受高效抗逆转录病毒治疗的状况,424名艾滋病毒感染者被纳入研究:115人尚未接受治疗,21人在入组前三个月内开始治疗,288人接受治疗至少12个月。通过世界卫生组织生活质量艾滋病毒简表评估生活质量。使用曼-惠特尼U检验、克鲁斯卡尔-沃利斯H检验、皮尔逊卡方检验或费舍尔精确检验进行统计比较。使用斯皮尔曼等级相关系数评估相关性。采用逻辑回归分析来检验生活质量得分与社会人口统计学或临床变量之间的关联。所有患者的生活质量平均总分为82.4。精神领域得分较高,环境领域得分较低。男性的总得分高于女性(p < 0.001)。文盲与较低的生活质量显著相关(p = 0.001)。获得医疗支持的患者生活质量明显更好(p < 0.01)。在多变量分析中,男性、获得医疗护理支持、年龄较大以及自我感觉健康与生活质量总得分高于77相关,这与我们数据中的得分中位数相对应。这些发现表明社会心理支持和良好环境对于改善艾滋病毒感染者生活质量的重要性,尤其是对于女性、年轻人以及那些没有医疗支持的人。在环境领域,艾滋病毒服务提供者的行动应侧重于更好地获得社会和医疗保健,促进创收活动,特别是针对感染艾滋病毒的妇女和青年。

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