Coe Charles, Bradley Arthur, Thibos Larry
*OD, PhD †PhD ‡PhD, FAAO Indiana University School of Optometry, Bloomington, Indiana (all authors).
Optom Vis Sci. 2014 Oct;91(10):1167-74. doi: 10.1097/OPX.0000000000000361.
To determine if measurement of monochromatic wavefront aberrations in near-infrared light can accurately and precisely predict subjective refractive error for polychromatic light. Our approach requires knowledge of the monochromatic wavelength-in-focus (WiF) when polychromatic light is well focused, for which new empirical measurements are reported.
With accommodation paralyzed, subjective refractive error was measured as a function of wavelength using a Badal optometer by optimally focusing a letter chart illuminated with monochromatic or white light (color temperature, 4575 K). Wavelength-in-focus was determined by interpolation as that wavelength for which monochromatic refractive error matches white light refractive error. The population-based mean value of WiF, used in conjunction with the Indiana Eye model of chromatic aberration, corrected for monochromatic (842 nm) estimates of refractive error obtained from wavefront aberration measurements, predicts the absolute refractive error of individual eye for polychromatic light for comparison with empirical measurements.
Average WiF for eight subjects was 569 nm (SE = 3.6 nm) for a 3-mm pupil and 575 nm (SE = 3.0 nm) for an 8-mm pupil. For small (3 mm) pupils, the mean (±SD) error in predicting refractive error for white light was 0.20 (±0.05) diopters (D) (range, +0.70 to -0.46 D), and for large (>8 mm) pupils, the mean (±SD) prediction error was 0.004 (±0.12) D (range, +0.56 to -0.52 D). The population mean of prediction errors was statistically not different from zero for large pupils but was slightly hyperopic for small pupils.
Subjective refractive error for white light can be accurately and precisely predicted objectively from monochromatic wavefront aberrations obtained for near-infrared light, but intersubject variability limits accuracy for individual subjects.
确定近红外光下单色波前像差测量能否准确且精确地预测多色光的主观屈光不正。我们的方法需要知道多色光聚焦良好时的单色聚焦波长(WiF),本文报告了对此进行的新的经验性测量。
在调节麻痹的情况下,使用巴达尔验光仪通过最佳聚焦用单色或白光(色温4575K)照明的字母视标,测量主观屈光不正随波长的变化。通过插值法确定聚焦波长,即单色屈光不正与白光屈光不正匹配时的波长。WiF的群体平均值与印第安纳眼色差模型相结合,对从波前像差测量中获得的单色(842nm)屈光不正估计值进行校正,预测个体眼睛多色光的绝对屈光不正,以便与经验性测量结果进行比较。
8名受试者3mm瞳孔的平均WiF为569nm(标准误=3.6nm),8mm瞳孔的平均WiF为575nm(标准误=3.0nm)。对于小(3mm)瞳孔,预测白光屈光不正的平均(±标准差)误差为0.20(±0.05)屈光度(D)(范围为+0.70至-0.46D),对于大(>8mm)瞳孔,平均(±标准差)预测误差为0.004(±0.12)D(范围为+0.56至-0.52D)。大瞳孔预测误差的群体平均值在统计学上与零无差异,但小瞳孔预测误差群体平均值略呈远视。
可以根据近红外光获得的单色波前像差客观、准确且精确地预测白光的主观屈光不正,但个体间的变异性限制了个体受试者的准确性。