Hunter Gary R, Plaisance Eric P, Fisher Gordon
Division of Kinesiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Curr Opin Endocrinol Diabetes Obes. 2014 Oct;21(5):358-62. doi: 10.1097/MED.0000000000000087.
Despite evidence that energy deficit produces multiple physiological and metabolic benefits, clinicians are often reluctant to prescribe weight loss in older individuals or those with low bone mineral density (BMD), fearing BMD will be decreased. Confusion exists concerning the effects that weight loss has on bone health.
Bone density is more closely associated with lean mass than total body mass and fat mass. Although rapid or large weight loss is often associated with loss of bone density, slower or smaller weight loss is much less apt to adversely affect BMD, especially when it is accompanied with high intensity resistance and/or impact loading training. Maintenance of calcium and vitamin D intake seems to positively affect BMD during weight loss. Although dual energy X-ray absorptiometry is normally used to evaluate bone density, it may overestimate BMD loss following massive weight loss. Volumetric quantitative computed tomography may be more accurate for tracking bone density changes following large weight loss.
Moderate weight loss does not necessarily compromise bone health, especially when exercise training is involved. Training strategies that include heavy resistance training and high impact loading that occur with jump training may be especially productive in maintaining, or even increasing bone density with weight loss.
尽管有证据表明能量不足会带来多种生理和代谢益处,但临床医生往往不愿为老年人或骨密度(BMD)低的患者开具减肥处方,担心骨密度会降低。关于减肥对骨骼健康的影响存在困惑。
骨密度与瘦体重的关联比与总体重和脂肪量更为密切。尽管快速或大量减肥通常与骨密度降低有关,但较慢或较小幅度的减肥对骨密度产生不利影响的可能性要小得多,尤其是在同时进行高强度抗阻和/或冲击负荷训练时。减肥期间维持钙和维生素D的摄入量似乎对骨密度有积极影响。尽管通常使用双能X线吸收法评估骨密度,但它可能会高估大量减肥后的骨密度损失。容积定量计算机断层扫描在跟踪大量减肥后的骨密度变化方面可能更准确。
适度减肥不一定会损害骨骼健康,尤其是在进行运动训练时。包括重负荷抗阻训练和跳跃训练中出现的高冲击负荷的训练策略,在减肥过程中维持甚至增加骨密度方面可能特别有效。