Hoashi Takaya, Yazaki Satoshi, Kagisaki Koji, Kitano Masataka, Kubota Sayaka Miura, Shiraishi Isao, Ichikawa Hajime
Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
J Cardiol. 2015 May;65(5):418-22. doi: 10.1016/j.jjcc.2014.07.009. Epub 2014 Aug 10.
This study aimed to review the single institutional experience of the repair of secundum atrial septal defect (ASD) after the initiation of percutaneous trans-catheter device closure, to confirm the current management strategy and outcomes.
From August 2005 to December 2012, a total of 1026 (659 females, age 27±21 years) consecutive patients underwent the repair of ASD. Including eight patients who converted to surgical repair, 317 patients (31%) underwent surgical repair and 709 (69%) underwent trans-catheter device closure.
An embolized device into the left atrium was surgically retrieved in one patient soon after trans-catheter device closure without any postoperative complications. The other patient developed left atrium to aorta fistula due to late erosion, and required the removal of implanted device and patch closure of fistula and ASD 3 months after trans-catheter device closure. Whereas serious central nerve system complications occurred in three patients after the surgical repair including a 75-year-old patient with postoperative transient atrial fibrillation who subsequently developed aspiration pneumonia and died; there were no mortalities and no morbidities associated with cranial nerve function after trans-catheter device closure. A number of patients approached through partial sternotomy with limited skin incision have increased per year, and the length of skin incision was 5.1±1.2cm in pediatric patients weighing less than 15kg (n=40), 6.9±1.9cm in the remaining pediatric patients (n=91), and 10.0±2.5cm in young adult females (n=10).
Percutaneous trans-catheter ASD closure was safely performed under the support of a surgical team. The cosmetic outcome of surgical closure is improving after initiation of partial sternotomy via limited skin incision for the pediatric population and young adult females. Prior to the treatment, the physicians must thoroughly inform patients and families of the advantages and disadvantages of both treatment options.
本研究旨在回顾经皮导管装置封堵术开展后继发孔房间隔缺损(ASD)修补的单机构经验,以确认当前的管理策略及结果。
2005年8月至2012年12月,共有1026例(659例女性,年龄27±21岁)连续性患者接受了ASD修补术。包括8例转为外科修补的患者,317例(31%)患者接受了外科修补,709例(69%)患者接受了经皮导管装置封堵术。
1例患者在经皮导管装置封堵术后不久,通过手术成功取出了栓塞入左心房的装置,无任何术后并发症。另1例患者因晚期侵蚀形成左心房至主动脉瘘,在经皮导管装置封堵术后3个月需要取出植入装置并修补瘘口及ASD。而在外科修补术后,3例患者出现了严重的中枢神经系统并发症,其中1例75岁患者术后发生短暂性心房颤动,随后并发吸入性肺炎死亡;经皮导管装置封堵术后无死亡病例,也无与颅神经功能相关的发病情况。每年通过部分胸骨切开术且皮肤切口有限的患者数量有所增加,体重小于15kg的儿科患者(n = 40)皮肤切口长度为5.1±1.2cm,其余儿科患者(n = 91)为6.9±1.9cm,年轻成年女性(n = 10)为10.0±2.5cm。
在外科团队的支持下,经皮导管ASD封堵术得以安全实施。对于儿科人群和年轻成年女性,通过有限皮肤切口进行部分胸骨切开术后,外科封堵的美容效果正在改善。在治疗前,医生必须向患者及其家属充分告知两种治疗方案的优缺点。