Grootjans-van Kampen Inge, Engelfriet Peter M, van Baal Pieter H M
Education and Student Affairs, Technical University, Delft, The Netherlands.
Centre for Prevention and Health Services Research, Institute for Public Health and the Environment, Bilthoven, The Netherlands.
PLoS One. 2014 Aug 12;9(8):e104469. doi: 10.1371/journal.pone.0104469. eCollection 2014.
Disease prevention has been claimed to reduce health care costs. However, preventing lethal diseases increases life expectancy and, thereby, indirectly increases the demand for health care. Previous studies have argued that on balance preventing diseases that reduce longevity increases health care costs while preventing non-fatal diseases could lead to health care savings. The objective of this research is to investigate if disease prevention could result in both increased longevity and lower lifetime health care costs.
Mortality rates for Netherlands in 2009 were used to construct cause-deleted life tables. Data originating from the Dutch Costs of Illness study was incorporated in order to estimate lifetime health care costs in the absence of selected disease categories. We took into account that for most diseases health care expenditures are concentrated in the last year of life.
Elimination of diseases that reduce life expectancy considerably increase lifetime health care costs. Exemplary are neoplasms that, when eliminated would increase both life expectancy and lifetime health care spending with roughly 5% for men and women. Costs savings are incurred when prevention has only a small effect on longevity such as in the case of mental and behavioural disorders. Diseases of the circulatory system stand out as their elimination would increase life expectancy while reducing health care spending.
The stronger the negative impact of a disease on longevity, the higher health care costs would be after elimination. Successful treatment of fatal diseases leaves less room for longevity gains due to effective prevention but more room for health care savings.
疾病预防被认为可以降低医疗成本。然而,预防致命疾病会延长预期寿命,从而间接增加对医疗保健的需求。先前的研究认为,总体而言,预防会缩短寿命的疾病会增加医疗成本,而预防非致命疾病可能会节省医疗费用。本研究的目的是调查疾病预防是否既能延长寿命又能降低终身医疗成本。
使用2009年荷兰的死亡率构建去除病因的生命表。纳入源自荷兰疾病成本研究的数据,以估计在没有选定疾病类别的情况下的终身医疗成本。我们考虑到,对于大多数疾病,医疗保健支出集中在生命的最后一年。
消除会大幅缩短预期寿命的疾病会大幅增加终身医疗成本。例如肿瘤,消除肿瘤会使男性和女性的预期寿命和终身医疗支出都增加约5%。当预防对寿命的影响很小时,如在精神和行为障碍的情况下,会产生成本节约。循环系统疾病很突出,因为消除这些疾病会增加预期寿命,同时降低医疗保健支出。
一种疾病对寿命的负面影响越强,消除后医疗成本就越高。致命疾病的成功治疗由于有效的预防而使寿命延长的空间变小,但医疗保健节省的空间变大。