甲型H1N1流感感染过程中的亚急性甲状腺炎
De Quervain thyroiditis in the course of H1N1 influenza infection.
作者信息
Michas G, Alevetsovitis G, Andrikou I, Tsimiklis S, Vryonis E
机构信息
Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece.
Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece ; North Middlesex University Hospital NHS Trust, London, UK.
出版信息
Hippokratia. 2014 Jan;18(1):86-7.
BACKGROUND/AIM: Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1 influenza infection.
DESCRIPTION OF THE CASE
A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase.
CONCLUSION
To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1 influenza infection.
背景/目的：病毒感染常与亚急性（德奎尔万氏）甲状腺炎及自身免疫性甲状腺疾病相关。在本病例报告中，我们记录了1例甲型H1N1流感感染过程中出现的罕见德奎尔万氏甲状腺炎病例。
病例描述
一名17岁、既往健康的女性在卡拉马塔综合医院接受治疗，出现了类似流感的综合征，伴有心悸、甲状腺肿大及C反应蛋白升高。聚合酶链反应检测确诊为甲型H1N1病毒感染。血清促甲状腺激素降至零，而游离甲状腺素和三碘甲状腺原氨酸水平升高。患者接受了非甾体抗炎药治疗，甲状腺功能逐渐恢复，未发展至甲状腺功能减退阶段。
结论
据我们所知，这是文献中描述的第二例与甲型H1N1流感感染相关的德奎尔万氏甲状腺炎病例。
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