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OLOGEN(®)植入物在Axenfeld-Rieger综合征罕见病例中用于青光眼治疗

OLOGEN(®) implant in the management of glaucoma in an unusual case of Axenfeld-Rieger syndrome.

作者信息

Radhakrishnan O K, Pahuja Kishore, Patel Khevna, Chandna Sunaina

机构信息

Department of Ophthalmology, Padmashree Dr. D. Y. Patil University Pimpri, Pune, Maharashtra, India.

Natasha Eyecare and Research Centre, Sai Saheb Bldg. Pimple Saudagar, Pune, Maharashtra, India.

出版信息

Oman J Ophthalmol. 2014 May;7(2):90-2. doi: 10.4103/0974-620X.137170.

Abstract

We report an unusual case of Axenfeld-Rieger Syndrome with secondary glaucoma managed with Ologen(®) implant. A 35-year-old male presented with complaints of decreased vision in both eyes of 22 years duration. His best corrected visual acuity (BCVA) was no perception of light in right eye and 20/30 in left eye. Gonioscopy revealed anterior insertion of iris into trabecular meshwork, prominent iris processes and broad-based synechiae with prominent Schwalbe's line along the angle circumference with cord-like structures taking its origin at the level of Schwalbe's line in both eyes. Fundus examination revealed total glaucomatous optic atrophy in right eye with 0.9:1 cup disc ratio with bipolar notch in left eye. Humphrey visual field analysis showed superior and inferior arcuate scotoma in left eye. Intraocular pressure measured by Goldman applanation tonometry was 30 mmHg and 26 mmHg in right and left eye, respectively. After an unsuccessful medical management, he underwent trabeculectomy with Ologen(®) implant under local anesthesia in his left eye. Postoperatively, at the end of one year, intraocular pressure (IOP) in his left eye was controlled without medication. This case highlights the management of secondary angle closure glaucoma in Axenfeld-Rieger syndrome with Ologen(®) implant.

摘要

我们报告了一例罕见的Axenfeld-Rieger综合征继发青光眼病例,采用Ologen(®)植入物进行治疗。一名35岁男性,双眼视力下降22年。他的最佳矫正视力(BCVA)右眼无光感,左眼为20/30。前房角镜检查显示虹膜向前插入小梁网,虹膜突明显,广泛的虹膜粘连,房角圆周处Schwalbe线明显,双眼在Schwalbe线水平有索状结构起源。眼底检查显示右眼完全性青光眼性视神经萎缩,杯盘比为0.9:1,左眼有双极切迹。Humphrey视野分析显示左眼有上下弓形暗点。用Goldmann压平眼压计测量的眼压右眼为30 mmHg,左眼为26 mmHg。药物治疗失败后,他在局部麻醉下左眼接受了小梁切除术并植入Ologen(®)植入物。术后一年末,他左眼眼压无需药物控制。该病例突出了采用Ologen(®)植入物治疗Axenfeld-Rieger综合征继发闭角型青光眼的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f72/4134556/3a4ad4d70bab/OJO-7-90-g001.jpg

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