《利兹消化不良问卷》中文版：评估亚洲人症状的有效工具。

Mandarin version of the Leeds Dyspepsia Questionnaire: A valid instrument for assessing symptoms in Asians.

作者信息

Leow Hwong-Ruey, Ching Siew-Mooi, Sujarita Ramanujam, Yap Choon-Fong, Chia Yook-Chin, Ho Shiaw-Hooi, Sithambaram Suresh, Tan Huck-Joo, Goh Khean-Lee, Mahadeva Sanjiv

机构信息

Division of Gastroenterology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

J Dig Dis. 2014 Nov;15(11):591-6. doi: 10.1111/1751-2980.12183.

DOI:10.1111/1751-2980.12183

PMID:25139629

Abstract

OBJECTIVE

To develop and validate a Mandarin version of the Leeds Dyspepsia Questionnaire (M-LDQ) in Asian patients with dyspepsia.

METHODS

The M-LDQ was developed according to standardized methods. The validity, internal consistency, test-retest reliability and responsiveness of the instrument were evaluated in both primary and secondary care patients.

RESULTS

A total of 184 patients (mean age 54.0 ± 15.8 years, of whom 59% were women and 72.3% of whom had at least secondary level education) were recruited between August 2012 and March 2013, from both primary (n = 100) and secondary care clinics (n = 84). Both the internal consistency of all components of the M-LDQ (Cronbach's α 0.79) and test-retest reliability (Spearman's correlation coefficient 0.78) were good. The M-LDQ was valid in diagnosing dyspepsia in primary care (area under the receiver operating characteristics curve 0.84) and was able to discriminate between secondary and primary care patients (median cumulative LDQ score 13.0 vs 3.0, P < 0.0001). Among eight patients with organic dyspepsia, the median M-LDQ score reduced significantly from 21.0 (pretreatment) to 9.5 (4 weeks post-treatment) (P < 0.0001).

CONCLUSION

The M-LDQ is a valid and responsive instrument for assessing ethnic Chinese adults with dyspepsia.

摘要

目的

开发并验证中文版利兹消化不良问卷（M-LDQ），用于亚洲消化不良患者。

方法

M-LDQ按照标准化方法开发。在初级和二级护理患者中评估该工具的效度、内部一致性、重测信度和反应度。

结果

2012年8月至2013年3月期间，共招募了184例患者（平均年龄54.0±15.8岁，其中59%为女性，72.3%至少接受过中等教育），来自初级护理诊所（n = 100）和二级护理诊所（n = 84）。M-LDQ所有分量表的内部一致性（Cronbach's α 0.79）和重测信度（Spearman相关系数0.78）均良好。M-LDQ在初级护理中诊断消化不良有效（受试者工作特征曲线下面积0.84），且能够区分二级护理和初级护理患者（LDQ累积得分中位数分别为13.0和3.0，P < 0.0001）。在8例器质性消化不良患者中，M-LDQ得分中位数从治疗前的21.0显著降至治疗后4周的9.5（P < 0.0001）。