由剧烈打鼾和血管紧张素转换酶抑制剂引起的悬雍垂孤立性水肿。
Isolated oedema of the uvula induced by intense snoring and ACE inhibitor.
作者信息
Rasmussen Eva Rye, Mey Kristianna, Bygum Anette
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, Koege Hospital, Koege, Denmark.
Department of Otorhinolaryngology and Audiology, University Hospital of Copenhagen, Rigshospitalet/Gentofte, Hellerup, Denmark.
出版信息
BMJ Case Rep. 2014 Aug 21;2014:bcr2014205585. doi: 10.1136/bcr-2014-205585.
Abstract
A case of snoring-induced angioedema of uvula is described in a patient who was treated with ACE inhibitor. The patient partially responded to complement C1-inhibitor concentrate and did not suffer any recurrences after the medication was withdrawn. When encountering a patient suffering from swellings of the orofacial area it should be considered whether the mechanism is mast-cell associated or not, as classical antiallergic treatment is ineffective in non-mast-cell-associated disease (ie, bradykinin-mediated angioedema). Other causes of uvular oedema are also discussed.
摘要
本文描述了一例使用血管紧张素转换酶（ACE）抑制剂治疗的患者出现打鼾诱发的悬雍垂血管性水肿的病例。该患者对补体C1抑制剂浓缩物有部分反应，停药后未再复发。当遇到口面部肿胀的患者时，应考虑其机制是否与肥大细胞相关，因为经典的抗过敏治疗对非肥大细胞相关疾病（即缓激肽介导的血管性水肿）无效。本文还讨论了悬雍垂水肿的其他原因。
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本文引用的文献
1
Images in clinical medicine. Isolated uvular angioedema.
N Engl J Med. 2014 Apr 10;370(15):e24. doi: 10.1056/NEJMicm1309447.
2
Angiotensin-converting enzyme inhibitor-induced angioedema--a dangerous new epidemic.
Acta Derm Venereol. 2014 May;94(3):260-4. doi: 10.2340/00015555-1760.
3
Male patient with throat swelling and painful swallowing.
J Emerg Med. 2013 Jun;44(6):1142-3. doi: 10.1016/j.jemermed.2012.11.060. Epub 2013 Apr 2.
4
Angioedema--assessment and treatment.
Tidsskr Nor Laegeforen. 2012 Nov 12;132(21):2391-5. doi: 10.4045/tidsskr.12.0470.
5
2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema.
Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):24. doi: 10.1186/1710-1492-6-24.
6
Edema of the uvula: etiology, risk factors, diagnosis, and treatment.
J Investig Allergol Clin Immunol. 2010;20(1):80-3.
7
Urticaria and infections.
Allergy Asthma Clin Immunol. 2009 Dec 1;5(1):10. doi: 10.1186/1710-1492-5-10.
8
Enlarged uvula (Quincke's Oedema)--a side effect of inhaled cocaine?--A case study and review of the literature.
Int Emerg Nurs. 2008 Jul;16(3):207-10. doi: 10.1016/j.ienj.2008.04.001. Epub 2008 Jun 10.
9
Multicenter study of patients with angiotensin-converting enzyme inhibitor-induced angioedema who present to the emergency department.
Ann Allergy Asthma Immunol. 2008 Apr;100(4):327-32. doi: 10.1016/S1081-1206(10)60594-7.
10
Life-threatening uvular angioedema caused by Ecbalium elaterium.
Eur J Emerg Med. 2001 Dec;8(4):337-9. doi: 10.1097/00063110-200112000-00018.
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