整合医学的临床试验：检验“魔法”是否有效？
Clinical trials of integrative medicine: testing whether magic works?
机构信息
Michael and Marian Ilitch Department of Surgery, Wayne State University School of Medicine, 3990 John R St., Detroit, MI 48201, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, 4100 John R St., Detroit, MI 48201, USA.
Department of Neurology, Yale University, 40 Temple St, Suite 6C, New Haven, CT 06510, USA.
出版信息
Trends Mol Med. 2014 Sep;20(9):473-6. doi: 10.1016/j.molmed.2014.06.007. Epub 2014 Aug 20.
Over the past two decades complementary and alternative medicine treatments relying on dubious science have been embraced by medical academia. Despite low to nonexistent prior probability that testing these treatments in randomized clinical trials (RCTs) will be successful, RCTs of these modalities have proliferated, consistent with the principles of evidence-based medicine, which underemphasize prior plausibility rooted in science. We examine this phenomenon and argue that what is needed is science-based medicine rather than evidence-based medicine.
在过去的二十年中，依赖可疑科学的补充和替代医学治疗方法已经被医学学术界所接受。尽管在随机临床试验 (RCT) 中测试这些治疗方法成功的可能性很低甚至不存在，但这些方法的 RCT 还是大量涌现，这与证据为基础的医学原则一致，该原则过分强调基于科学的先前合理性。我们研究了这一现象，并认为需要的是基于科学的医学而不是基于证据的医学。
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