Lester Barry M, Andreozzi-Fontaine Lynne, Tronick Edward, Bigsby Rosemarie
Center for the Study of Children at Risk, Alpert Medical School, Brown University; Women & Infants Hospital of Rhode Island;
Center for the Study of Children at Risk, Alpert Medical School, Brown University; Women & Infants Hospital of Rhode Island.
J Vis Exp. 2014 Aug 25(90):3368. doi: 10.3791/3368.
There has been a long-standing interest in the assessment of the neurobehavioral integrity of the newborn infant. The NICU Network Neurobehavioral Scale (NNNS) was developed as an assessment for the at-risk infant. These are infants who are at increased risk for poor developmental outcome because of insults during prenatal development, such as substance exposure or prematurity or factors such as poverty, poor nutrition or lack of prenatal care that can have adverse effects on the intrauterine environment and affect the developing fetus. The NNNS assesses the full range of infant neurobehavioral performance including neurological integrity, behavioral functioning, and signs of stress/abstinence. The NNNS is a noninvasive neonatal assessment tool with demonstrated validity as a predictor, not only of medical outcomes such as cerebral palsy diagnosis, neurological abnormalities, and diseases with risks to the brain, but also of developmental outcomes such as mental and motor functioning, behavior problems, school readiness, and IQ. The NNNS can identify infants at high risk for abnormal developmental outcome and is an important clinical tool that enables medical researchers and health practitioners to identify these infants and develop intervention programs to optimize the development of these infants as early as possible. The video shows the NNNS procedures, shows examples of normal and abnormal performance and the various clinical populations in which the exam can be used.
长期以来,人们一直对评估新生儿的神经行为完整性感兴趣。新生儿重症监护病房网络神经行为量表(NNNS)是作为对高危婴儿的一种评估工具而开发的。这些婴儿由于产前发育期间受到伤害,如接触有害物质、早产,或诸如贫困、营养不良或缺乏产前护理等因素,而面临发育不良后果的风险增加,这些因素会对子宫内环境产生不利影响并影响发育中的胎儿。NNNS评估婴儿神经行为表现的各个方面,包括神经完整性、行为功能以及应激/戒断迹象。NNNS是一种非侵入性的新生儿评估工具,已被证明不仅作为脑瘫诊断、神经异常以及脑部有风险疾病等医学结果的预测指标有效,而且作为心理和运动功能、行为问题、入学准备和智商等发育结果的预测指标也有效。NNNS可以识别发育结果异常的高危婴儿,是一种重要的临床工具,使医学研究人员和健康从业者能够识别这些婴儿,并尽早制定干预计划以优化这些婴儿的发育。该视频展示了NNNS的操作流程,展示了正常和异常表现的示例以及可使用该检查的各种临床人群。