鞘内注射巴氯芬在儿童和青少年中的应用：2013年跨学科共识表
Use of intrathecal baclofen in children and adolescents: interdisciplinary consensus table 2013.
作者信息
Berweck Steffen, Lütjen Sonnhild, Voss Wolfgang, Diebold Uta, Mücke Karl-Heinz, Aisch Angelika, Ostertag Bernhart, Friedrich Monika, Wagner Christiane, Kudernatsch Manfred, Granel Michael, Kluger Gerhard, Ludwikowski Barbara, Peraud Aurelia, Rauchenzauner Markus, Schroeder A Sebastian, Sprinz Andreas, Wienand Rieke, Wilken Bernd, Kästner Stefanie, Zeches Caroline, Mall Volker
机构信息
Department of Paediatric Neurology and Rehabilitation, Epilepsy Center for Children and Adults, Schön Clinic Vogtareuth, Vogtareuth, Germany.
Neuropaediatric Outpatient Center, Children's Hospital Auf Der Bult, Hannover, Germany.
出版信息
Neuropediatrics. 2014 Oct;45(5):294-308. doi: 10.1055/s-0034-1387818. Epub 2014 Sep 4.
In recent years, intrathecal baclofen (ITB) has attained an important role in the treatment of severe spasticity and dystonia in children. There are principal differences between the use of ITB in children and its use in neurology and oncology in adults. Here, we present a consensus report on best practice for the treatment of severe spastic and dystonic movement disorders with ITB. Using a problem-orientated approach to integrate theories and methods, the consensus was developed by an interdisciplinary group of experienced ITB users and experts in the field of movement disorders involving 14 German centers. On the basis of the data pooled from more than 400 patients, the authors have summarized their experience and supporting evidence in tabular form to provide a concise, but still a comprehensive information base that represents our current understanding regarding ITB treatment options in children and adolescents.
近年来，鞘内注射巴氯芬（ITB）在治疗儿童严重痉挛和肌张力障碍方面发挥了重要作用。ITB在儿童中的应用与在成人神经病学和肿瘤学中的应用存在主要差异。在此，我们提出一份关于使用ITB治疗严重痉挛和肌张力障碍性运动障碍的最佳实践共识报告。通过采用以问题为导向的方法来整合理论和方法，由来自14个德国中心的经验丰富的ITB使用者和运动障碍领域专家组成的跨学科小组达成了这一共识。基于从400多名患者汇总的数据，作者以表格形式总结了他们的经验和支持证据，以提供一个简洁但仍全面的信息库，代表我们目前对儿童和青少年ITB治疗选择的理解。
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