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综合征型和非综合征型儿童采用Furlow腭成形术进行黏膜下腭裂一期修复的结果

Results of Primary Repair of Submucous Cleft Palate With Furlow Palatoplasty in Both Syndromic and Nonsyndromic Children.

作者信息

Ng Zhi Yang, Young Selena Ee-Li, Por Yong Chen, Yeow Vincent

出版信息

Cleft Palate Craniofac J. 2015 Sep;52(5):525-31. doi: 10.1597/14-179. Epub 2014 Sep 5.

Abstract

OBJECTIVE

We hypothesize that primary repair of submucous cleft palate (SMCP) with Furlow palatoplasty will not lead to significant differences in speech outcomes for syndromic and nonsyndromic children.

DESIGN

Retrospective analysis of patients with primary Furlow repair of SMCP between 2004 and 2012.

SETTING

Tertiary care center.

PATIENTS/PARTICIPANTS: Thirty-four patients (15 boys; 44%) satisfied our inclusion criteria: multidisciplinary consensus on diagnosis of SMCP, failed trial of speech-language rehabilitation, at least 4 years old at the time of primary surgery, at least 6 months follow-up with a repeat set of postoperative speech assessments.

INTERVENTIONS

Primary Furlow palatoplasty for SMCP.

MAIN OUTCOME MEASURES

Primary outcomes were based on postoperative perceptual speech assessments and the need for revision surgery. Secondary outcomes included improvement in nasalance scores, postoperative complications, and change in and time to normalization of velar closing ratios.

RESULTS

Mean age at surgery = 7.7 years. Of the patients, 17 (50%) were syndromic and 11 (32%) had associated hearing loss. Mean follow-up = 48 months. No patients had postoperative complications, such as wound dehiscence or fistula; however, two patients (one syndromic, one nonsyndromic) required secondary procedures. Velar closing ratios for all patients increased (P < .05) and approached normal at an average of 1.3 years postoperatively.

CONCLUSIONS

Although the Furlow palatoplasty can correct anatomic anomalies, it cannot achieve normal perceptual resonance in syndromic patients, possibly because of inherent higher-order deficiencies that affect speech production. Further studies with greater patient numbers are necessary to achieve population statistical significance.

摘要

目的

我们假设采用Furlow腭成形术对黏膜下腭裂(SMCP)进行一期修复,对于综合征型和非综合征型儿童而言,在言语结局方面不会导致显著差异。

设计

对2004年至2012年间接受SMCP一期Furlow修复术的患者进行回顾性分析。

地点

三级医疗中心。

患者/参与者:34名患者(15名男孩;44%)符合我们的纳入标准:对SMCP诊断达成多学科共识、言语语言康复试验失败、初次手术时至少4岁、术后至少随访6个月并进行一组重复的术后言语评估。

干预措施

对SMCP进行一期Furlow腭成形术。

主要结局指标

主要结局基于术后感知言语评估以及再次手术的必要性。次要结局包括鼻音评分的改善、术后并发症以及腭关闭率的变化和恢复正常的时间。

结果

手术时的平均年龄为7.7岁。患者中,17名(50%)为综合征型,11名(32%)伴有听力损失。平均随访时间为48个月。没有患者出现术后并发症,如伤口裂开或瘘管;然而,两名患者(一名综合征型,一名非综合征型)需要二次手术。所有患者的腭关闭率均有所提高(P < 0.05),术后平均1.3年接近正常。

结论

尽管Furlow腭成形术可以纠正解剖异常,但对于综合征型患者无法实现正常的感知共鸣,这可能是由于影响言语产生的内在高阶缺陷所致。需要进行更多患者数量的进一步研究以达到总体统计学显著性。

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