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短期佩戴微型巩膜接触镜后的角膜变化。

Corneal changes following short-term miniscleral contact lens wear.

作者信息

Vincent Stephen J, Alonso-Caneiro David, Collins Michael J

机构信息

Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Australia.

Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Australia.

出版信息

Cont Lens Anterior Eye. 2014 Dec;37(6):461-8. doi: 10.1016/j.clae.2014.08.002. Epub 2014 Sep 5.

Abstract

PURPOSE

To examine the influence of short-term miniscleral contact lens wear on corneal shape, thickness and anterior surface aberrations.

METHODS

Scheimpflug imaging was captured before, immediately following and 3h after a short period (3h) of miniscleral contact lens wear for 10 young (mean 27±5 years), healthy participants. Natural diurnal variations were considered by measuring baseline diurnal changes obtained on a separate control day without contact lens wear.

RESULTS

Small but significant anterior corneal flattening was observed immediately following lens removal (overall mean 0.02±0.03mm, p<0.001) which returned to baseline levels 3h after lens removal. During the 3h recovery period significant corneal thinning (-13.4±10.5μm) and posterior surface flattening (0.03±0.02mm) were also observed (both p<0.01). The magnitude of posterior corneal flattening during recovery correlated with the amount of corneal thinning (r=0.69, p=0.03). Central corneal clearance (maximum tear reservoir depth) was not associated with corneal swelling following lens removal (r=-0.24, p>0.05). An increase in lower-order corneal astigmatism Z(2,2) was also observed following lens wear (mean -0.144±0.075μm, p=0.02).

CONCLUSIONS

Flattening of the anterior corneal surface was observed immediately following lens wear, while 'rebound' thinning and flattening of the posterior surface was evident following the recovery period. Modern miniscleral contact lenses that vault the cornea may slightly influence corneal shape and power but do not induce clinically significant corneal oedema during short-term wear.

摘要

目的

研究短期佩戴迷你巩膜接触镜对角膜形状、厚度及前表面像差的影响。

方法

对10名年轻(平均27±5岁)健康受试者,在佩戴迷你巩膜接触镜3小时的短期过程中,于佩戴前、佩戴后即刻及佩戴后3小时进行Scheimpflug成像。通过测量在无接触镜佩戴的单独对照日获得的基线昼夜变化来考虑自然昼夜变化。

结果

摘除镜片后即刻观察到角膜前表面有微小但显著的变平(总体平均值0.02±0.03mm,p<0.001),在摘除镜片后3小时恢复到基线水平。在3小时的恢复期内,还观察到角膜显著变薄(-13.4±10.5μm)和后表面变平(0.03±0.02mm)(均p<0.01)。恢复期间角膜后表面变平的程度与角膜变薄的量相关(r=0.69,p=0.03)。摘除镜片后中央角膜间隙(最大泪液储存深度)与角膜肿胀无关(r=-0.24,p>0.05)。佩戴镜片后还观察到低阶角膜散光Z(2,2)增加(平均值-0.144±0.075μm,p=0.02)。

结论

佩戴镜片后即刻观察到角膜前表面变平,而恢复期后后表面出现“反弹”变薄和变平。使角膜呈拱形的现代迷你巩膜接触镜可能会对角膜形状和屈光力有轻微影响,但在短期佩戴期间不会引起临床上显著的角膜水肿。

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