Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, the Influenza Division, National Center for Immunization and Respiratory Diseases, the National Center for Emerging and Zoonotic Infectious Diseases, and the Office of Public Health Preparedness and Response, Centers for Disease Control and Prevention, Atlanta, Georgia.
Obstet Gynecol. 2014 Nov;124(5):1005-1010. doi: 10.1097/AOG.0000000000000533.
West Africa is currently in the midst of the largest Ebola outbreak in history. Although there have been no Ebola virus disease cases identified in the United States, two U.S. health care workers with Ebola virus disease were medically evacuated from Liberia to the United States in early August 2014. The Centers for Disease Control and Prevention has been working closely with other U.S. government agencies and international and nongovernmental partners for several months to respond to this global crisis. Limited evidence suggests that pregnant women are at increased risk for severe illness and death when infected with Ebola virus, but there is no evidence to suggest that pregnant women are more susceptible to Ebola virus disease. In addition, pregnant women with Ebola virus disease appear to be at an increased risk for spontaneous abortion and pregnancy-associated hemorrhage. Neonates born to mothers with Ebola virus disease have not survived. Although it is very unlikely that obstetrician-gynecologists (ob-gyns) in the United States will diagnose or treat a patient with Ebola virus disease, it is important that all health care providers are prepared to evaluate and care for these patients. Specifically, U.S. health care providers, including ob-gyns, should ask patients about recent travel and should know the signs and symptoms of Ebola virus disease and what to do if assessing a patient with compatible illness. This article provides general background information on Ebola and specifically addresses what is known about Ebola virus disease in pregnancy and the implications for practicing ob-gyns in the United States.
西非目前正处于历史上最大规模的埃博拉疫情之中。尽管在美国尚未发现埃博拉病毒病病例,但 2014 年 8 月初,两名患有埃博拉病毒病的美国医护人员从利比里亚被医疗后送回美国。美国疾病控制与预防中心(Centers for Disease Control and Prevention)已与其他美国政府机构、国际组织和非政府组织合作了数月,以应对这一全球危机。有限的证据表明,孕妇感染埃博拉病毒后发生重症和死亡的风险增加,但没有证据表明孕妇更容易感染埃博拉病毒病。此外,患有埃博拉病毒病的孕妇自发性流产和妊娠相关出血的风险似乎增加。感染埃博拉病毒病的母亲所生新生儿均未能存活。虽然在美国,妇产科医生(ob-gyns)极不可能诊断或治疗埃博拉病毒病患者,但所有医护人员都应做好准备评估和护理这些患者是很重要的。具体而言,美国医护人员,包括妇产科医生,应询问患者近期的旅行情况,并应了解埃博拉病毒病的症状和体征,如果评估有疑似该病的患者应如何处理。本文提供了有关埃博拉的一般背景信息,并特别针对妊娠期埃博拉病毒病的已知情况以及对美国妇产科医生的影响进行了讨论。