Adv Exp Med Biol. 2014;810:342-58. doi: 10.1007/978-1-4939-0437-2_19.
Solar UV radiation (UVR) exposure is clearly associated with increased mortality from nonmelanoma skin cancer--usually squamous cell carcinoma. However, the association with cutaneous melanoma is unclear from the evidence in ecologic studies and several analytic studies have conflicting results regarding the effect of high levels of intermittent UV exposure prior to diagnosis on mortality. Understanding this conundrum is critical to present coherent public health messages and to improve the mortality rates from melanoma.
太阳紫外线(UVR)辐射暴露显然与非黑色素瘤皮肤癌(通常为鳞状细胞癌)的死亡率增加有关。然而,从生态学研究的证据来看,与皮肤黑色素瘤的关联并不明确,并且一些分析研究对于诊断前间歇性高水平紫外线暴露对死亡率的影响存在相互矛盾的结果。理解这一难题对于提出连贯的公共卫生信息和提高黑色素瘤死亡率至关重要。