钌红-多壁碳纳米管修饰玻碳电极用于同时测定肾上腺素和对乙酰氨基酚的研究
Development of glassy carbon electrode modified with ruthenium red-multiwalled carbon nanotubes for simultaneous determination of epinephrine and acetaminophen.
作者信息
Nadiki Hadi Hassani, Noroozifar Meissam, Khorasani-Motlagh Mozhgan
机构信息
Department of Chemistry, University of Sistan and Baluchestan.
出版信息
Anal Sci. 2014;30(9):911-8. doi: 10.2116/analsci.30.911.
A glassy carbon electrode modified with ruthenium red and functionalized multi-walled carbon nanotube has been developed. The electrochemical response characteristics of the modified electrode toward epinephrine (EP) and acetaminophen (AC) was investigated by differential pulse voltammetry (DPV). Linear calibration plots were obtained over the range of 0.3 - 333.3 μM for both EP and AC with sensitivities of 0.221 and 0.174 μA μM(-1) for EP and AC, respectively. The detection limits for EP and AC were 0.04 and 0.06 μM, respectively. The diffusion coefficients for the oxidation of EP and AC at the modified electrode were calculated as 2.74 ± 0.05 × 10(-5) and 1.75 ± 0.07 × 10(-5) cm(2) s(-1), respectively. The practical analytical utilities of the modified electrode were demonstrated by the determination of EP and AC in human urine and serum as well as AC tablet samples.
已开发出一种用钌红和功能化多壁碳纳米管修饰的玻碳电极。采用差分脉冲伏安法（DPV）研究了修饰电极对肾上腺素（EP）和对乙酰氨基酚（AC）的电化学响应特性。在0.3 - 333.3 μM范围内获得了EP和AC的线性校准曲线，EP和AC的灵敏度分别为0.221和0.174 μA μM⁻¹。EP和AC的检测限分别为0.04和0.06 μM。计算出EP和AC在修饰电极上氧化的扩散系数分别为2.74 ± 0.05 × 10⁻⁵和1.75 ± 0.07 × 10⁻⁵ cm² s⁻¹。通过测定人尿液、血清以及AC片剂样品中的EP和AC，证明了修饰电极的实际分析效用。
Zotero 插件