Yamane Hideo, Iguchi Hiroyoshi, Konishi Kazuo, Sakamaoto Hiramori, Wada Tadashi, Fujioka Takanori, Matsushita Naoki, Imoto Toshio
Department of Otolaryngology, Osaka City University Graduate School of Medicine , Osaka , Japan.
Acta Otolaryngol. 2014 Oct;134(10):1016-21. doi: 10.3109/00016489.2014.913315.
Three-dimensional cone beam computed tomography (3DCT) images revealed characteristic malformations of the membranous labyrinth of the inner ear in Meniere's disease (MD). The morphology of the membranous region between the vestibular cecum of the cochlea and the saccule of ears with MD was compared to that of healthy ears. The present study supports the hypothesis proposed earlier that reuniting duct blockade is a result of the dislodgement of saccular otoconia.
To visualize the membranous labyrinth using 3DCT and to investigate the pathology of MD.
A preparatory study was conducted to determine the optimal 3DCT window settings for the detection of water, muscle, calcium carbonate (CaCO3), and bone. Based on this preparatory study, the ears of 13 healthy volunteers and 25 MD patients definitely diagnosed according to the criteria issued by the Committee on Hearing and Equilibrium of the American Academy of Otolaryngology, Head and Neck Surgery (AAO-HNS), were visualized.
The differences in the membranous labyrinth between MD ears and healthy ears could be visualized using 3DCT. The images were classified into three types based on their morphological pattern. The ears of patients with MD were different from normal ears in terms of this classification.
三维锥形束计算机断层扫描（3DCT）图像显示了梅尼埃病（MD）患者内耳膜迷路的特征性畸形。将MD患者耳蜗前庭盲端与球囊之间膜性区域的形态与健康耳朵进行了比较。本研究支持了先前提出的假说，即联合管阻塞是球囊耳石移位的结果。
使用3DCT可视化膜迷路并研究MD的病理。
进行了一项预备研究，以确定检测水、肌肉、碳酸钙（CaCO3）和骨骼的最佳3DCT窗口设置。基于这项预备研究，对13名健康志愿者和25名根据美国耳鼻咽喉头颈外科学会（AAO-HNS）听力与平衡委员会发布的标准明确诊断为MD的患者的耳朵进行了可视化。
使用3DCT可以可视化MD耳朵和健康耳朵之间膜迷路的差异。根据形态模式将图像分为三种类型。MD患者的耳朵在这种分类方面与正常耳朵不同。
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