Liu Jung-Tai, Yeh Horng-Ming, Liu Shyun-Yeu, Chen Kow-Tong
Jung-Tai Liu, Department of Physical Medicine and Rehabilitation, Chi-Mei Medical Center, Liouying, Tainan 736, Taiwan.
World J Orthop. 2014 Sep 18;5(4):537-43. doi: 10.5312/wjo.v5.i4.537.
Our understanding of psoriatic arthritis has evolved as new knowledge of the disease has emerged. However, the exact prevalence of psoriatic arthritis is unknown, and its pathogenesis has not been fully elucidated. Genetic, environmental, and immunologic factors have all been implicated in disease development. Early diagnosis and treatment have become primary objectives in clinical rheumatology. Psoriatic arthritis not only causes functional impairment, but also increases mortality risk of patients. The advent of new therapeutic agents capable of arresting the progression of joint damage is expected. However, early psoriatic arthritis assessment remains limited. The objectives of this article are to outline the epidemiology, diagnosis, and treatment of psoriatic arthritis and to suggest a paradigm for identifying early psoriatic arthritis patients.
随着对银屑病关节炎的新知识不断涌现,我们对它的理解也在不断发展。然而,银屑病关节炎的确切患病率尚不清楚,其发病机制也尚未完全阐明。遗传、环境和免疫因素都与疾病的发展有关。早期诊断和治疗已成为临床风湿病学的主要目标。银屑病关节炎不仅会导致功能障碍,还会增加患者的死亡风险。有望出现能够阻止关节损伤进展的新型治疗药物。然而,早期银屑病关节炎的评估仍然有限。本文的目的是概述银屑病关节炎的流行病学、诊断和治疗,并提出一种识别早期银屑病关节炎患者的模式。