Sprenger Katharina, Evison John Marc, Zwahlen Marcel, Vogt Cedric M, Elzi Maria Verena, Hauser Christoph, Furrer Hansjakob, Low Nicola
Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland.
Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
PeerJ. 2014 Aug 26;2:e537. doi: 10.7717/peerj.537. eCollection 2014.
Sexually transmitted infections (STI) in HIV-infected people are of increasing concern. We estimated STI prevalence and sexual healthcare seeking behaviour in 224 sexually active HIV-infected people, including men who have sex with men (MSM, n = 112), heterosexual men (n = 65) and women (n = 47). Laboratory-diagnosed bacterial STI were more common in MSM (Chlamydia trachomatis 10.7%; 95% CI 6.2, 18.0%, lymphogranuloma venereum 0.9%; 95% CI 0.1, 6.2%, Neisseria gonorrhoeae 2.7%; 95% CI 0.9, 8.0%, syphilis seroconversion 5.4%; 95% CI 2.0, 11.3%) than heterosexual men (gonorrhoea 1.5%; 95% CI 0.2, 10.3%) or women (no acute infections). Combined rates of laboratory-diagnosed and self-reported bacterial STI in the year before the study were: MSM (27.7%; 95% CI 21.1, 36.7%); heterosexual men (1.5%; 95% CI 0.2, 10.3%); and women (6.4%; 95% CI 2.1, 21.0%). Antibodies to hepatitis C virus were least common in MSM. Antibodies to herpes simplex type 2 virus were least common in heterosexual men. Most MSM, but not heterosexual men or women, agreed that STI testing should be offered every year. In this study, combined rates of bacterial STI in MSM were high; a regular assessment of sexual health would allow those at risk of STI to be offered testing, treatment and partner management.
感染艾滋病毒者的性传播感染(STI)问题日益受到关注。我们估计了224名性活跃的感染艾滋病毒者的性传播感染患病率及寻求性健康护理行为,其中包括男男性行为者(MSM,n = 112)、异性恋男性(n = 65)和女性(n = 47)。实验室诊断的细菌性性传播感染在男男性行为者中更为常见(沙眼衣原体10.7%;95%置信区间6.2,18.0%,性病性淋巴肉芽肿0.9%;95%置信区间0.1,6.2%,淋病奈瑟菌2.7%;95%置信区间0.9,8.0%,梅毒血清转化5.4%;95%置信区间2.0,11.3%),高于异性恋男性(淋病1.5%;95%置信区间0.2,10.3%)或女性(无急性感染)。研究前一年实验室诊断和自我报告的细菌性性传播感染综合发生率为:男男性行为者(27.7%;95%置信区间21.1,36.7%);异性恋男性(1.5%;95%置信区间0.2,10.3%);女性(6.4%;95%置信区间2.1,21.0%)。丙型肝炎病毒抗体在男男性行为者中最不常见。2型单纯疱疹病毒抗体在异性恋男性中最不常见。大多数男男性行为者,但不是异性恋男性或女性,同意应每年进行性传播感染检测。在本研究中,男男性行为者的细菌性性传播感染综合发生率较高;定期评估性健康状况将使性传播感染风险人群能够接受检测、治疗及性伴管理。