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伴有水泡状动脉瘤的蛛网膜下腔出血:血管内治疗

Subarachnoid hemorrhage with blister aneurysms: Endovascular management.

作者信息

Chinchure Swati Dayanand, Gupta Vipul, Goel Gaurav, Gupta Aditya, Jha Ajayanand

机构信息

Department of Interventional Neuroradiology, Institute of Neurosciences, Medanta- the Medicity, Gurgaon, Haryana, India.

出版信息

Neurol India. 2014 Jul-Aug;62(4):393-9. doi: 10.4103/0028-3886.141262.

Abstract

UNLABELLED

Blister aneurysms of are rare lesions representing a real challenge for diagnosis and management. They typically show small size, hemispherical shape, fragile wall, broad neck, and are arising from non-branching sites of intracranial arteries.

MATERIALS AND METHODS

We retrospectively reviewed all aneurysms treated at our institution. Seventeen patients (6 male, 11 female) with 17 blister aneurysms were identified (mean age 53.3, range 41-63 years). Clinical, procedural, angiographic data as well as follow up data were evaluated.

RESULTS

All patients presented with aneurysmal subarachnoid hemorrhage. Majority of the blister aneurysms were located in ICA while 1 was located at posterior cerebral artery, 1 at vertebral and 1 involving basilar artery. All patients were treated using single or overlapping stents and if possible additional coiling. There was no intra-operative rupture. Good outcome (mrs 0-2) was seen in 14 patients. Poor clinical outcome (mrs 3-5) was seen in 2 patients due to vasospasm induced ischemic deficits at discharge, both of them improved on follow up (mrs 1 on follow up). There were 3 mortalities, One patient died of rebleeding while other 2 died due to SAH induced complications. Follow-up angiography was available in 16 patients (one patient died before follow up angiogram) and revealed complete or near complete aneurysm occlusion in 11, incomplete obliteration in 1 and no change in 2 cases. Two cases showed post-treatment angiographic aneurysm recurrence. Both cases were managed with repeat coiling and overlapping stent placement.

CONCLUSION

Endovascular management using single/overlapping stent and if possible coil placement is technically safe and feasible in blister aneurysms. Overlapping stents lead to better aneurysm occlusion than a single stent. Blister aneurysm in dorso-medial ICA showed higher tendency of continued growth/recurrence, higher incidence of clinical vasospasm and in these cases early angiographic follow-up is advisable. Repeat treatment should be considered promptly if necessary.

摘要

未标注

水泡状动脉瘤是罕见病变,对诊断和治疗构成真正挑战。它们通常体积小、呈半球形、壁脆弱、颈部宽,且起源于颅内动脉的非分支部位。

材料与方法

我们回顾性分析了在我院接受治疗的所有动脉瘤病例。确定了17例患有17个水泡状动脉瘤的患者(6例男性,11例女性)(平均年龄53.3岁,范围41 - 63岁)。评估了临床、手术、血管造影数据以及随访数据。

结果

所有患者均表现为动脉瘤性蛛网膜下腔出血。大多数水泡状动脉瘤位于颈内动脉,1个位于大脑后动脉,1个位于椎动脉,1个累及基底动脉。所有患者均采用单个或重叠支架治疗,如有可能还进行了额外的弹簧圈栓塞。术中无破裂发生。14例患者预后良好(改良Rankin量表评分0 - 2分)。2例患者临床预后较差(改良Rankin量表评分3 - 5分),出院时因血管痉挛导致缺血性神经功能缺损,随访时均有所改善(随访时改良Rankin量表评分1分)。有3例死亡,1例患者死于再出血,另外2例死于蛛网膜下腔出血引起的并发症。16例患者有随访血管造影结果(1例患者在随访血管造影前死亡),其中11例显示动脉瘤完全或近乎完全闭塞,1例不完全闭塞,2例无变化。2例显示治疗后血管造影动脉瘤复发。这2例均通过重复弹簧圈栓塞和重叠支架置入进行处理。

结论

对于水泡状动脉瘤,采用单个/重叠支架并在可能时进行弹簧圈置入的血管内治疗在技术上是安全可行的。重叠支架比单个支架能更好地闭塞动脉瘤。颈内动脉背内侧的水泡状动脉瘤显示出更高的持续生长/复发倾向、更高的临床血管痉挛发生率,在这些情况下建议早期进行血管造影随访。如有必要应及时考虑重复治疗。

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