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脑动静脉畸形中的出血性碰撞转移

Hemorrhagic collision metastasis in a cerebral arteriovenous malformation.

作者信息

Sundarakumar Dinesh K, Marshall Desiree A, Keene C Dirk, Rockhill Jason K, Margolin Kim A, Kim Louis J

机构信息

Department of Radiology, University of Washington, Seattle, Washington, USA.

Department of Pathology, University of Washington, Seattle, Washington, USA.

出版信息

BMJ Case Rep. 2014 Sep 19;2014:bcr2014011362. doi: 10.1136/bcr-2014-011362.

Abstract

A 26-year-old patient with recurrent choriocarcinoma of the testis presented with headache and progressive left homonymous hemianopsia. On initial MRI a grade 4 arteriovenous malformation (AVM) was identified in the right occipital lobe, which was further characterized by catheter angiography. Continued worsening of the headache in the following days prompted a follow-up MRI, which revealed a new T2 hypointense nodule and adjacent vasogenic edema in the periphery of the AVM. A follow-up MRI showed a marked increase in the size of the nodule with intrinsic enhancement and worsening perilesional edema. Based on the imaging evolution, the nodule was diagnosed as a metastasis and the patient was started on chemotherapy and radiotherapy. One week after the MRI he developed a sudden hemorrhage within the mass requiring decompression craniectomy and resection of both AVM and tumor. The histopathology of the resected mass confirmed the diagnosis of choriocarcinoma metastasis to the AVM.

摘要

一名26岁复发性睾丸绒毛膜癌患者出现头痛和进行性左侧同向性偏盲。初次MRI检查时,在右侧枕叶发现1个4级动静脉畸形(AVM),通过导管血管造影进一步明确其特征。接下来几天头痛持续加重,促使进行了一次随访MRI检查,结果显示在AVM周边出现1个新的T2低信号结节及相邻的血管源性水肿。后续的MRI检查显示结节大小显著增加,有内部强化,且病灶周围水肿加重。根据影像学变化,该结节被诊断为转移瘤,患者开始接受化疗和放疗。MRI检查一周后,肿块内突然出血,需要进行减压颅骨切除术,并切除AVM和肿瘤。切除肿块的组织病理学检查证实为绒毛膜癌转移至AVM。

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