Bourne Sarah, Machado Andre G, Nagel Sean J
Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, S4, Cleveland, OH 44195, USA.
Department of Neurosurgery, Center for Neurological Restoration, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue, S31, Cleveland, OH 44195, USA.
Neurosurg Clin N Am. 2014 Oct;25(4):629-38. doi: 10.1016/j.nec.2014.06.001. Epub 2014 Aug 3.
This article provides an integrated review of the basic anatomy and physiology of the pain processing pathways. The transmission and parcellation of noxious stimuli from the peripheral nervous system to the central nervous system is discussed. In addition, the inhibitory and excitatory systems that regulate pain along with the consequences of dysfunction are considered.
本文对疼痛传导通路的基本解剖学和生理学进行了综合综述。文中讨论了有害刺激从外周神经系统到中枢神经系统的传递和划分。此外,还考虑了调节疼痛的抑制性和兴奋性系统以及功能障碍的后果。