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疼痛传导通路的基础解剖学与生理学

Basic anatomy and physiology of pain pathways.

作者信息

Bourne Sarah, Machado Andre G, Nagel Sean J

机构信息

Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, S4, Cleveland, OH 44195, USA.

Department of Neurosurgery, Center for Neurological Restoration, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue, S31, Cleveland, OH 44195, USA.

出版信息

Neurosurg Clin N Am. 2014 Oct;25(4):629-38. doi: 10.1016/j.nec.2014.06.001. Epub 2014 Aug 3.

DOI:10.1016/j.nec.2014.06.001
PMID:25240653
Abstract

This article provides an integrated review of the basic anatomy and physiology of the pain processing pathways. The transmission and parcellation of noxious stimuli from the peripheral nervous system to the central nervous system is discussed. In addition, the inhibitory and excitatory systems that regulate pain along with the consequences of dysfunction are considered.

摘要

本文对疼痛传导通路的基本解剖学和生理学进行了综合综述。文中讨论了有害刺激从外周神经系统到中枢神经系统的传递和划分。此外,还考虑了调节疼痛的抑制性和兴奋性系统以及功能障碍的后果。

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