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初潮年龄是否受体重指数和脂蛋白谱的影响?一项回顾性研究。

Whether age of menarche is influenced by body mass index and lipoproteins profile? a retrospective study.

作者信息

Farahmand Maryam, Ramezani Tehrani Fahimeh, Azizi Fereidoun

机构信息

Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Obstetrics and Gynecology, Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Reprod Med. 2012 Jul;10(4):337-42.

Abstract

BACKGROUND

Menarche, a milestone in the reproductive life span of a woman, is influenced by several genetics and environmental factors. There is no consensus regarding the impact of body mass index (BMI) and lipid profiles on the age of menarche, as the results of various studies demonstrate.

OBJECTIVE

To investigate the correlation between age of menarche and BMI/lipoprotein profile in a community sample of Iranian girls.

MATERIALS AND METHODS

In the study, 370 girls, aged 10-16 years, who began their menarche within six months prior to the study, were recruited from the Tehran Lipid and Glucose Study (TLGS) population. Information was documented regarding their body composition, including height, weight, BMI, waist and hip circumference were collected and their lipid profiles were assessed after a 12-hour fast.

RESULTS

In this study, the mean±SD of age of menarche and BMI were 12.6±1.1 years and 21.7±3.9 kg/m(2), respectively. There were statistically significant relationships between age of menarche and height, BMI, waist circumference, and the maternal educational level. The relationship between age of menarche and the weight and lipid profiles of subjects was not statistically significant.

CONCLUSION

Age at menarche is not influenced by lipid profiles but it is influenced by BMI.

摘要

背景

月经初潮是女性生殖寿命中的一个里程碑,受到多种遗传和环境因素的影响。正如各项研究结果所示,关于体重指数(BMI)和血脂谱对月经初潮年龄的影响尚无共识。

目的

在伊朗女孩的社区样本中研究月经初潮年龄与BMI/脂蛋白谱之间的相关性。

材料与方法

在本研究中,从德黑兰血脂与血糖研究(TLGS)人群中招募了370名年龄在10 - 16岁之间、在研究前六个月内开始月经初潮的女孩。记录了她们的身体组成信息,包括身高、体重、BMI、腰围和臀围,并在禁食12小时后评估她们的血脂谱。

结果

在本研究中,月经初潮年龄和BMI的平均值±标准差分别为12.6±1.1岁和21.7±3.9 kg/m²。月经初潮年龄与身高、BMI、腰围和母亲教育水平之间存在统计学上的显著关系。月经初潮年龄与受试者的体重和血脂谱之间的关系无统计学意义。

结论

月经初潮年龄不受血脂谱影响,但受BMI影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc7a/4165951/537a8fd4dd31/ijrm-10-337-g001.jpg

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