Iamaroon Arissara, Tangwiwat Suwimon, Sirivanasandha Busara, Halilamien Pathom, Lertpenmetha Yada, Sirimaneewattana Saroj, Surachetpong Sudkanoung, Puangchan Supranee
J Med Assoc Thai. 2014 Jul;97(7):717-23.
Femoral nerve block (FNB) with varying concentrations of bupivacaine is often used for postoperative analgesia after anterior cruciate ligament (ACL) reconstruction.
To determine whether FNB using 0.25% or 0.5% bupivacaine provided better analgesia with less effect on quadriceps strengths after ACL reconstruction.
One hundred patients were randomized to receive FNB with 20 mL of 0.25% or 0.5% bupivacaine. Data regarding demographic, effectiveness of FNB, time to first pain, time to first analgesic, pain scores, morphine use, and recovery of sensory and motor function were recorded.
Median time to first morphine requirement was 12 hours in 0.5% bupivacaine group and 10 hours in 0.25% bupivacaine group (p = 0.048). Pain score at 18 hours was lower in 0.5% bupivacaine group compared with 0.25% bupivacaine group (p = 0.001). When specify to the patellar tendon graft subgroup, the patients requiring morphine were 70% in 0.5% bupivacaine group and 90% in 0.25% bupivacaine group (p = 0.03). No differences were found in demographic data, effectiveness of FNB, time to first pain, morphine consumption, and recovery of sensorimotor function.
FNB with 0.5% bupivacaine provided longer time to first analgesic and lower narcotic requirements after patellar tendon graft ACL reconstruction when compared to 0.25% bupivacaine. Both concentrations showed similar effect on quadriceps strengths.
不同浓度布比卡因的股神经阻滞(FNB)常用于前交叉韧带(ACL)重建术后的镇痛。
确定在ACL重建术后,使用0.25%或0.5%布比卡因的FNB是否能提供更好的镇痛效果,同时对股四头肌力量的影响更小。
100例患者被随机分为两组,分别接受20毫升0.25%或0.5%布比卡因的FNB。记录患者的人口统计学数据、FNB的效果、首次疼痛时间、首次使用镇痛药时间、疼痛评分、吗啡使用情况以及感觉和运动功能的恢复情况。
0.5%布比卡因组首次需要吗啡的中位时间为12小时,0.25%布比卡因组为10小时(p = 0.048)。0.5%布比卡因组18小时时的疼痛评分低于0.25%布比卡因组(p = 0.001)。在髌腱移植亚组中,0.5%布比卡因组需要吗啡的患者为70%,0.25%布比卡因组为90%(p = 0.03)。在人口统计学数据、FNB效果、首次疼痛时间、吗啡消耗量以及感觉运动功能恢复方面未发现差异。
与0.25%布比卡因相比,在髌腱移植ACL重建术后,0.5%布比卡因的FNB提供了更长的首次镇痛时间和更低的麻醉药需求量。两种浓度对股四头肌力量的影响相似。