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新鲜冷冻同种异体股骨头的成本分析:运营骨库是否值得?

Cost analysis of fresh-frozen femoral head allografts: is it worthwhile to run a bone bank?

作者信息

Benninger E, Zingg P O, Kamath A F, Dora C

机构信息

Balgrist University Hospital, Department of Orthopaedics, University of Zurich, Forchstrasse 340, 8008 Zürich, Switzerland.

Pennsylvania Hospital , Department of Orthopaedic Surgery, 800 Spruce Street, Philadelphia, 19107, USA.

出版信息

Bone Joint J. 2014 Oct;96-B(10):1307-11. doi: 10.1302/0301-620X.96B10.33486.

Abstract

To assess the sustainability of our institutional bone bank, we calculated the final product cost of fresh-frozen femoral head allografts and compared these costs with the use of commercial alternatives. Between 2007 and 2010 all quantifiable costs associated with allograft donor screening, harvesting, storage, and administration of femoral head allografts retrieved from patients undergoing elective hip replacement were analysed. From 290 femoral head allografts harvested and stored as full (complete) head specimens or as two halves, 101 had to be withdrawn. In total, 104 full and 75 half heads were implanted in 152 recipients. The calculated final product costs were €1367 per full head. Compared with the use of commercially available processed allografts, a saving of at least €43 119 was realised over four-years (€10 780 per year) resulting in a cost-effective intervention at our institution. Assuming a price of between €1672 and €2149 per commercially purchased allograft, breakeven analysis revealed that implanting between 34 and 63 allografts per year equated to the total cost of bone banking.

摘要

为评估我们机构骨库的可持续性,我们计算了新鲜冷冻股骨头同种异体移植物的最终产品成本,并将这些成本与使用商业替代品的成本进行了比较。在2007年至2010年期间,分析了与同种异体移植物供体筛查、采集、储存以及从接受择期髋关节置换术的患者中获取的股骨头同种异体移植物管理相关的所有可量化成本。从290个作为完整(全)头标本或两半储存的收获的股骨头同种异体移植物中,有101个不得不被撤回。总共,104个全头和75个半头被植入152名接受者体内。计算得出的最终产品成本为每个全头1367欧元。与使用市售加工同种异体移植物相比,四年内实现了至少43119欧元的节省(每年10780欧元),从而在我们机构实现了具有成本效益的干预措施。假设每个商业购买的同种异体移植物价格在1672欧元至2149欧元之间,盈亏平衡分析表明,每年植入34至63个同种异体移植物等同于骨库的总成本。

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