长叶薄荷的乙酸乙酯提取物和水提取物以及多花百里香的水醇提取物对重要人类病原体的抗菌活性。
Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens.
作者信息
Saeidi Saeide, Hassanpour Kazem, Ghamgosha Mehdi, Heiat Mohammad, Taheri Ramezan Ali, Mirhosseini Ali, Farnoosh Gholamreza
机构信息
Department of Agronomy and Plant Breeding, Agriculture Research Center, Zabol University, Zabol, Iran.
Medical School, Sabzevar University of Medical Sciences, Sabzevar, Iran.
出版信息
Asian Pac J Trop Med. 2014 Sep;7S1:S186-9. doi: 10.1016/S1995-7645(14)60229-7.
OBJECTIVE
To determine the potential antibacterial activity of ethyl acetate and aqueous extracts from Mentha longifolia L. (M. longifolia) and hydroalcoholic extract of Zataria multiflora Boiss. (Z. multiflora) against important human pathogens.
METHODS
Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella pneumoniae (K. pneumonia), Enterobacter cloacae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Staphylococcus saprophyticus and Staphylococcus aureus were kinds of pathogenic bacteria to determine the antibacterial effect of aqueous and ethyl acetate extracts of M. longifolia and hydroalcoholic extract of Z. multiflora using broth microdiluation method.
RESULTS
The lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Pseudomonas aeruginosa (1.25 and 2.5 mg/mL) were observed by the hydroalcoholic extract of Z. multiflora and the lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Serratia marcescens (2.5 and 5 mg/mL) were observed by the aqueous extracts of M. longifolia.
CONCLUSIONS
In conclusion, it seems that Z. multiflora and M. longifolia extracts could inhibit the growth of all of the mentioned bacteria.
目的
测定长叶薄荷（Mentha longifolia L.，M. longifolia）的乙酸乙酯提取物和水提取物以及多花百里香（Zataria multiflora Boiss.，Z. multiflora）的水醇提取物对重要人类病原体的潜在抗菌活性。
方法
铜绿假单胞菌、痢疾志贺菌、肺炎克雷伯菌（K. pneumonia）、阴沟肠杆菌、伤寒沙门菌、奇异变形杆菌、粘质沙雷氏菌、蜡样芽孢杆菌、腐生葡萄球菌和金黄色葡萄球菌是用于采用肉汤微量稀释法测定长叶薄荷水提取物和乙酸乙酯提取物以及多花百里香水醇提取物抗菌效果的病原菌种类。
结果
多花百里香水醇提取物对肺炎克雷伯菌和铜绿假单胞菌观察到最低的最低抑菌浓度和最低杀菌浓度值（分别为1.25和2.5 mg/mL），长叶薄荷水提取物对肺炎克雷伯菌和粘质沙雷氏菌观察到最低的最低抑菌浓度和最低杀菌浓度值（分别为2.5和5 mg/mL）。
结论
总之，似乎多花百里香和长叶薄荷提取物能够抑制所有上述细菌的生长。
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