[8;21易位与白血病]
[8;21 translocation and leukemia].
作者信息
Rochon M, Vaillancourt L, Lépine J, Lépine-Martin M, Longpré B, Boutan-Laroze A
出版信息
Union Med Can. 1989 Nov-Dec;118(6):238-41.
PMID:2532428
Abstract
The authors report their observations on acute myeloid leukemias associated with the 8;21 translocation. Two cases have less than the required percentage of blasts for the cytological diagnosis of acute myeloid leukemia. In one case, the 8;21 translocation is superimposed on a constitutional trisomy 21. Conclusions from the 4th International Workshop on chromosomes in leukemia are highlighted, as well as certain new data relative to the biology of acute myeloid leukemias.
摘要
作者报告了他们对与8;21易位相关的急性髓系白血病的观察结果。两例患者的原始细胞百分比低于急性髓系白血病细胞学诊断所需的百分比。在一例中，8;21易位叠加在一个21号染色体三体的体质性异常上。文中突出了第四届白血病染色体国际研讨会的结论，以及与急性髓系白血病生物学相关的某些新数据。
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