慢性嗜中性粒细胞白血病：一例罕见病例报告。

Chronic neutrophilic leukemia: a rare case report.

作者信息

Rane Sharada R, Kulkarni Maithili M, Puranik Shaila C

机构信息

Pathology Department, BJ Medical College, Pune, India ; Pathology Department, BJ Medical College, Pune, India.

Pathology Department, BJ Medical College, Pune, India ; E 401, Samrajya, Shivtirthnagar, Paud Road, Pune, India.

出版信息

Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):77-9. doi: 10.1007/s12288-013-0254-3. Epub 2013 Apr 26.

DOI:10.1007/s12288-013-0254-3

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4192157/

Abstract

Chronic neutrophilic leukemia (CNL) is a rare chronic myeloproliferative disorder characterized by splenomegaly, sustained neutrophilic leukocytosis, raised serum vitamin B12 level and absence of the Philadelphia chromosome and BCR/ABL1 fusion gene. CNL can be distinguished from chronic myelogenous leukemia, leukemoid reaction and myelodysplastic syndrome. We report a case of 45 year old male patient with CNL.

摘要

慢性中性粒细胞白血病（CNL）是一种罕见的慢性骨髓增殖性疾病，其特征为脾肿大、持续性中性粒细胞增多、血清维生素B12水平升高以及无费城染色体和BCR/ABL1融合基因。CNL可与慢性粒细胞白血病、类白血病反应和骨髓增生异常综合征相鉴别。我们报告一例45岁男性慢性中性粒细胞白血病患者。

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