Minamide Akihito, Yoshida Munehito, Yamada Hiroshi, Nakagawa Yukihiro, Hashizume Hiroshi, Iwasaki Hiroshi, Tsutsui Shunji
Department of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama, 641-8510, Japan,
Eur Spine J. 2015 Feb;24(2):396-403. doi: 10.1007/s00586-014-3599-x. Epub 2014 Oct 24.
To prospectively investigate the long-term clinical outcomes of microendoscopic laminotomy (MEL) in patients with lumbar spinal stenosis (LSS) with and without degenerative spondylolisthesis (DS).
In total, 159 patients (mean age, 68 years) who had undergone MEL for single-level LSS at L4/5 at our institute were recruited and followed-up for 5 years. Patients with and without DS were assigned to the DS (n = 71) and control (n = 88) groups, respectively. In addition to slippage rate, Japanese orthopedic association (JOA), recovery rate, short-form 36 (SF-36), and Roland-Morris disability questionnaire (RDQ) values were evaluated preoperatively and 5 years postoperatively. All parameters were analyzed by Student's t test, with p < 0.05 considered statistically significant.
Of 159 patients, 12 were lost to follow-up (follow-up rate, 92.5%); moreover, 15 patients were excluded because of death, cerebral infarction, dementia, or terminal cancer. Thus, 132 patients (DS group: 61, control group: 71) were finally examined. No significant differences were found in preoperative JOA, JOA recovery rate, RDQ, and SF-36 values between groups. The slippage rate in the DS group was 18.1% preoperatively and 16.8% at 5 years postoperatively (p > 0.05). There was no significant increase in instability in those with DS following MEL. Progressive spinal instability was noted in six patients (9.8%) and five patients (7.0 %) in the DS and control groups, respectively (p > 0.05). Moreover, the success rate of MEL was good/excellent in 70%, fair in 20%, and poor in 10 % of patients in both groups.
MEL showed similar outcomes in patients with DS and in those without DS.
前瞻性研究微型内镜下椎板切除术(MEL)治疗伴有或不伴有退变性腰椎滑脱(DS)的腰椎管狭窄症(LSS)患者的长期临床疗效。
本研究共纳入159例在我院接受L4/5单节段LSS的MEL手术患者(平均年龄68岁),并进行了5年随访。伴有和不伴有DS的患者分别被分配到DS组(n = 71)和对照组(n = 88)。除滑脱率外,术前及术后5年评估日本骨科协会(JOA)评分、恢复率、简明健康状况调查量表(SF-36)及罗兰-莫里斯功能障碍问卷(RDQ)评分。所有参数采用Student's t检验进行分析,p < 0.05认为具有统计学意义。
159例患者中,12例失访(随访率92.5%);此外,15例因死亡、脑梗死、痴呆或晚期癌症被排除。最终对132例患者(DS组:61例,对照组:71例)进行了检查。两组术前JOA评分、JOA恢复率、RDQ评分及SF-36评分差异均无统计学意义。DS组术前滑脱率为18.1%,术后5年为16.8%(p > 0.05)。MEL术后DS患者的不稳定性无显著增加。DS组和对照组分别有6例(9.8%)和5例(7.0%)患者出现进行性脊柱不稳(p > 0.05)。此外,两组患者中MEL手术成功率为优的占70%,良的占20%,差的占10%。
MEL治疗伴有DS和不伴有DS的患者疗效相似。