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使用可摘式下颌神经假体减轻创伤后应激障碍(PTSD)以及轻度创伤性脑损伤/PTSD/相关噩梦、头痛和睡眠障碍。

Use of a Removable Mandibular Neuroprosthesis for the Reduction of Posttraumatic Stress Disorder (PTSD) and Mild Traumatic Brain Injury/PTSD/Associated Nightmares, Headaches, and Sleep Disturbances.

作者信息

Moeller Donald R, Duffey John M, Goolsby Angela M, Gallimore Jesse T

出版信息

J Spec Oper Med. 2014 Fall;14(3):64-73. doi: 10.55460/MHVO-MN5Q.

Abstract

INTRODUCTION

Posttraumatic stress disorder (PTSD) has been associated with nighttime headaches (HAs), nightmares (NMs), and difficulty falling or staying asleep (sleep disturbances [SD]). The authors of the current study evaluated the correlative elements of using a removable mandibular neuroprosthesis (RMN) and the reduction of these symptoms in participants diagnosed with PTSD or mild traumatic brain injury (mTBI)/PTSD. The RMN device is a form of specialized dental splint that has a potential to reduce the painful stimuli of bruxing and potential upregulation of threat response systems that may occur during sleep.

METHOD

A sample of 32 individuals was selected through random assignment from a volunteer base of 200 volunteers for examination by self-report according to an A-B-A-B design. The sample included 25 men and 7 women between the ages of 21 and 65; 21 had military experience and 11 were civilians. Participants were asked to rate the frequency and intensity of their HAs, NMs, and SD during each phase. Their responses were scored using a custom survey (equivalent forms reliability) that provides ratio-scaled results for symptom frequency and intensity. The original number of participants was 35 with three participants dropping out before the conclusion of the study.

RESULTS

Survey scores for PTSD-related sleep symptoms were relatively high at baseline (x̄=0.52) and significantly lower in the first experimental phase (x̄=0.20). Scores in the second experimental phase were likewise lower (x̄=0.38). Significant reductions in symptoms were reported across all three dimensions.

DISCUSSION

All participants reported some improvement in symptoms while using the device. No participants reported worsening of any symptoms as a result of using the RMN. Participants commonly reported that improvements in symptoms were immediate and did not diminish over time. Data indicate that there is a negative correlation between the use of an RMN and the reduction of HAs, NMs, and SD in persons diagnosed with PTSD or mTBI/PTSD.

摘要

引言

创伤后应激障碍(PTSD)与夜间头痛(HA)、噩梦(NM)以及入睡困难或睡眠维持困难(睡眠障碍[SD])有关。本研究的作者评估了使用可摘式下颌神经假体(RMN)的相关因素,以及在被诊断为PTSD或轻度创伤性脑损伤(mTBI)/PTSD的参与者中这些症状的减轻情况。RMN装置是一种特殊的牙夹板形式,有可能减少磨牙的疼痛刺激以及睡眠期间可能发生的威胁反应系统的潜在上调。

方法

根据A - B - A - B设计,从200名志愿者的志愿者库中随机抽取32名个体进行自我报告检查。样本包括25名男性和7名女性,年龄在21岁至65岁之间;21人有军事经历,11人是平民。要求参与者在每个阶段对其HA、NM和SD的频率和强度进行评分。他们的回答使用定制调查问卷(等效形式信度)进行评分,该问卷为症状频率和强度提供比率量表结果。最初的参与者人数为35人,有3名参与者在研究结束前退出。

结果

与PTSD相关的睡眠症状的调查分数在基线时相对较高(x̄ = 0.52),在第一个实验阶段显著较低(x̄ = 0.20)。第二个实验阶段的分数同样较低(x̄ = 0.38)。所有三个维度的症状均有显著减轻。

讨论

所有参与者在使用该装置时均报告症状有所改善。没有参与者报告因使用RMN而导致任何症状恶化。参与者普遍报告症状改善是即时的,且不会随时间减弱。数据表明,在被诊断为PTSD或mTBI/PTSD的人群中,使用RMN与HA、NM和SD的减轻之间存在负相关。

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