Attaallah Wafi, Ertekin Caglar, Tinay Ilker, Yegen Cumhur
Department of General Surgery, Marmara University School of Medicine, Istanbul, Turkey.
Department of Urology, Marmara University School of Medicine, Istanbul, Turkey.
Ann Coloproctol. 2014 Oct;30(5):210-5. doi: 10.3393/ac.2014.30.5.210. Epub 2014 Oct 28.
Although rectal cancer is a very common malignancy and has an improved cure rate in response to oncological treatment, research on rectal-cancer survivors' sexual function remains limited. Sexual dysfunction (SD) after rectal cancer treatment was measured, and possible predisposing factors that may have an impact on the development of this disorder were identified.
Patients undergoing curative rectal cancer surgery from January 2012 to September 2013 were surveyed using questionnaires. The female sexual function index or the International Index of Erectile Function was recorded. A multiple logistic regression was used to test associations of clinical factors with outcomes.
Fifty-six men (56%) and 28 women (44%) who completed the questionnaire were included in the study. A total of 76 patients of the 86 patients (90.5%) with the diagnosis of rectal cancer who were included in this study reported different levels of SD after radical surgery. A total of 64 patients (76%) from the whole cohort reported moderate to severe SD after treatment of rectal cancer. Gender (P = 0.011) was independently associated with SD. Female patients reported significantly higher rates of moderate to severe SD than male patients. Patients were rarely treated for dysfunction.
Sexual problems after surgery for rectal cancer are common, but patients are rarely treated for SD. Female patients reported higher rates of SD than males. These results point out the importance of sexual (dys)function in survivors of rectal cancer. More attention should be drawn to this topic for clinical and research purposes.
尽管直肠癌是一种非常常见的恶性肿瘤,并且肿瘤治疗后的治愈率有所提高,但关于直肠癌幸存者性功能的研究仍然有限。我们对直肠癌治疗后的性功能障碍(SD)进行了测量,并确定了可能影响该疾病发生的潜在诱发因素。
采用问卷调查的方式对2012年1月至2013年9月期间接受根治性直肠癌手术的患者进行了调查。记录女性性功能指数或国际勃起功能指数。采用多元逻辑回归分析来检验临床因素与结果之间的关联。
完成问卷调查的56名男性(56%)和28名女性(44%)被纳入研究。本研究纳入的86例诊断为直肠癌的患者中,共有76例(90.5%)在根治性手术后报告了不同程度的性功能障碍。整个队列中共有64例患者(76%)在直肠癌治疗后报告有中度至重度性功能障碍。性别(P = 0.011)与性功能障碍独立相关。女性患者报告的中度至重度性功能障碍发生率显著高于男性患者。患者很少因性功能障碍接受治疗。
直肠癌手术后的性功能问题很常见,但患者很少因性功能障碍接受治疗。女性患者报告的性功能障碍发生率高于男性。这些结果指出了性功能(障碍)在直肠癌幸存者中的重要性。出于临床和研究目的,应更多地关注这一话题。