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门诊手术后1周内术后患者疼痛与恶心的关系。

The Relationship of Pain and Nausea in Postoperative Patients for 1 Week After Ambulatory Surgery.

作者信息

Odom-Forren Jan, Rayens Mary K, Gokun Yevgeniya, Jalota Leena, Radke Oliver, Hooper Vallire, Wiggins Amanda T, Apfel Christian C

机构信息

*College of Nursing, University of Kentucky, Lexington, KY †University of California ‡Department of Anesthesia and Perioperative Care, University of California, San Francisco General Hospital ¶Associate Adjunct Professor, Department of Epidemiology & Biostatistics, University of California, San Francisco, CA §Department of Anesthesiology and Critical Care Medicine, University Hospital Carl Gustav Carus Dresden at the TU Dresden, Fetscherstr, Dresden ∥Medical College of Georgia, Augusta, GA.

出版信息

Clin J Pain. 2015 Oct;31(10):845-51. doi: 10.1097/AJP.0000000000000170.

Abstract

OBJECTIVES

The purpose of this study was to determine if pain level was associated with demographic or surgery-specific characteristics among patients recovering from ambulatory surgery; and to assess the relationship between pain level and nausea over the 7-day postoperative period, controlling for demographic and surgery-related covariates.

MATERIALS AND METHODS

This longitudinal study assessed the pain and nausea of 248 eligible patients during the day of surgery (DOS) and the 7 days following ambulatory surgery. Postoperative data were assessed using standardized questions about severity of pain and nausea symptoms. Participants who had a cumulative pain score of ≥24 over the 8-day period were categorized as having high pain. Repeated-measures analysis of variance was used to assess differences in nausea by pain group over time, controlling for demographic, surgical variables, and antiemetic and analgesic use.

RESULTS

There were significant differences between 2 pain groups in age, surgical procedure, cumulative morphine equivalent dose, and use of antiemetics postdischarge. The longitudinal analysis demonstrated that patients in the high-pain group reported a greater degree of nausea on DOS and on each of the first 5 days postsurgery, controlling for differences in age, sex, education, use of antiemetics presurgery and postsurgery, use of acetaminophen postsurgery, daily morphine equivalent dose, and surgical procedure.

DISCUSSION

Younger patients and those receiving orthopedic procedures may be at greatest risk for postoperative pain. Patients with high pain reported a significantly greater degree of nausea on DOS through the first 5 days postdischarge. As the majority of surgeries are now conducted in the ambulatory setting, it is imperative that we determine pain management regimens and patient education practices that will allow for a more comfortable recovery for our patients.

摘要

目的

本研究旨在确定门诊手术后恢复过程中患者的疼痛程度是否与人口统计学特征或手术特定特征相关;并评估术后7天内疼痛程度与恶心之间的关系,同时控制人口统计学和手术相关协变量。

材料与方法

这项纵向研究评估了248例符合条件的患者在手术当天(DOS)及门诊手术后7天的疼痛和恶心情况。术后数据通过关于疼痛和恶心症状严重程度的标准化问题进行评估。在8天期间累积疼痛评分≥24分的参与者被归类为疼痛程度高。采用重复测量方差分析来评估不同疼痛组随时间的恶心差异,同时控制人口统计学、手术变量以及止吐药和镇痛药的使用情况。

结果

两个疼痛组在年龄、手术方式、累积吗啡当量剂量以及出院后止吐药的使用方面存在显著差异。纵向分析表明,在控制年龄、性别、教育程度、术前和术后止吐药的使用、术后对乙酰氨基酚的使用、每日吗啡当量剂量和手术方式等差异后,高疼痛组患者在手术当天及术后前5天的每一天报告的恶心程度更高。

讨论

年轻患者和接受骨科手术的患者术后疼痛风险可能最高。疼痛程度高的患者在出院后第1天至第5天报告的恶心程度明显更高。由于目前大多数手术在门诊进行,我们必须确定能够让患者更舒适恢复的疼痛管理方案和患者教育方法。

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