定义慢性肾脏病进展的新替代标志物。
Defining new surrogate markers for CKD progression.
作者信息
Schnaper H William, Furth Susan L, Yao Lynne P
机构信息
Department of Pediatrics, Northwestern University Feinberg School of Medicine, Morton Building Room 4-685G, 320 E. Superior, Chicago, IL, 60611, USA,
出版信息
Pediatr Nephrol. 2015 Feb;30(2):193-8. doi: 10.1007/s00467-014-2995-0. Epub 2014 Nov 5.
Abstract
At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.
摘要
在最近一次关于慢性进行性肾脏病（CKD）临床方面的国际专家会议上，对现有临床试验进行了广泛分析，以开发出更有效、更经济的成人CKD预后替代标志物。本文介绍了开展此项工作的原因、会议的方法和结论，以及这些发现与儿科肾脏病学的相关性。
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