Internal Medicine, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba.
Section of Infectious Diseases, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba.
Can J Infect Dis Med Microbiol. 2014 Sep;25(5):e85-6. doi: 10.1155/2014/802481.
Eggerthella lenta is an anaerobic, Gram-positive bacillus commonly found in the human digestive tract. Occasionally, it can cause life-threatening infections. Bacteremia due to this organism is always clinically significant and is associated with gastrointestinal diseases and states of immune suppression. The authors report a case involving an elderly man with a newly diagnosed gastrointestinal malignancy who developed bacteremia caused by E lenta, treated successfully using empirical therapy with vancomycin and piperacillin-tazobactam, followed by directed therapy with metronidazole once the identity and antibiotic susceptibility of the organism was established. The present case reinforces the connection between E lenta bacteremia with gastrointestinal malignancy and highlights the importance of searching for a source of bacteremia due to this organism.
迟缓埃格特菌是一种常见于人类消化道的厌氧性革兰阳性杆菌。偶尔，它可引起危及生命的感染。由该菌引起的菌血症总是具有临床意义，并与胃肠道疾病和免疫抑制状态有关。作者报告了一例老年男性，患有新诊断的胃肠道恶性肿瘤，发生了由迟缓埃格特菌引起的菌血症，经验性使用万古霉素和哌拉西林他唑巴坦治疗获得成功，随后在确定该菌的身份和抗生素敏感性后，使用甲硝唑进行靶向治疗。本病例再次强调了迟缓埃格特菌菌血症与胃肠道恶性肿瘤之间的联系，并强调了寻找该菌引起菌血症源的重要性。
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