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乳糜泻和非乳糜泻形式的麸质敏感:一种古老疾病的范式转变

Celiac and Non-Celiac Forms of Gluten Sensitivity: Shifting Paradigms of an Old Disease.

作者信息

Sestak Karol, Fortgang Ilana

机构信息

Division of Microbiology, Tulane National Primate Research Center and Tulane University School of Medicine, 18703 Three Rivers Road, Covington, LA 70433, USA.

Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, Tulane Hospital for Children, 1415 Tulane Avenue, New Orleans, LA 70112, USA.

出版信息

Br Microbiol Res J. 2013 Oct;3(4):585-589. doi: 10.9734/BMRJ/2013/6083.

Abstract

Gluten sensitivity is one of the prominent features of celiac disease (CD) which is an autoimmune disorder characterized by damaged lining of the small intestine. CD was known already to ancient Greeks as κοιλιακός () i.e. disease of the abdominal cavity hence celiac. Focus of this Commentary article is on rather complex definition of CD and its emerging new forms the example of which is non-celiac gluten sensitivity. It is becoming evident that to formulate more effective treatments, these associations and newly identified disease entities deserve attention from both academic and clinical communities.

摘要

麸质敏感性是乳糜泻(CD)的突出特征之一,乳糜泻是一种自身免疫性疾病,其特征是小肠内壁受损。古希腊人就已经知道CD,称之为κοιλιακός(即腹腔疾病,因此称为乳糜泻)。这篇评论文章的重点是CD相当复杂的定义及其新出现的形式,其中一个例子就是非乳糜泻性麸质敏感性。越来越明显的是,为了制定更有效的治疗方法,这些关联和新发现的疾病实体值得学术界和临床界的关注。

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