Cecconi Maurizio, De Backer Daniel, Antonelli Massimo, Beale Richard, Bakker Jan, Hofer Christoph, Jaeschke Roman, Mebazaa Alexandre, Pinsky Michael R, Teboul Jean Louis, Vincent Jean Louis, Rhodes Andrew
Anaesthesia and Intensive Care, St George's Hospital and Medical School, SW17 0QT, London, UK,
Intensive Care Med. 2014 Dec;40(12):1795-815. doi: 10.1007/s00134-014-3525-z. Epub 2014 Nov 13.
Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
The European Society of Intensive Care Medicine invited 12 experts to form a Task Force to update a previous consensus (Antonelli et al.: Intensive Care Med 33:575-590, 2007). The same five questions addressed in the earlier consensus were used as the outline for the literature search and review, with the aim of the Task Force to produce statements based on the available literature and evidence. These questions were: (1) What are the epidemiologic and pathophysiologic features of shock in the intensive care unit? (2) Should we monitor preload and fluid responsiveness in shock? (3) How and when should we monitor stroke volume or cardiac output in shock? (4) What markers of the regional and microcirculation can be monitored, and how can cellular function be assessed in shock? (5) What is the evidence for using hemodynamic monitoring to direct therapy in shock? Four types of statements were used: definition, recommendation, best practice and statement of fact.
Forty-four statements were made. The main new statements include: (1) statements on individualizing blood pressure targets; (2) statements on the assessment and prediction of fluid responsiveness; (3) statements on the use of echocardiography and hemodynamic monitoring.
This consensus provides 44 statements that can be used at the bedside to diagnose, treat and monitor patients with shock.
循环性休克是一种危及生命的综合征,可导致多器官功能衰竭和高死亡率。本共识的目的是为床边临床医生在休克的诊断、管理和监测方面提供支持。
欧洲重症医学学会邀请12位专家组成一个特别工作组,以更新先前的共识(Antonelli等人:《重症医学》33:575 - 590,2007年)。早期共识中提出的相同五个问题被用作文献检索和综述的大纲,特别工作组的目的是根据现有文献和证据制定声明。这些问题是:(1)重症监护病房中休克的流行病学和病理生理学特征是什么?(2)我们是否应该在休克中监测前负荷和液体反应性?(3)我们应该如何以及何时在休克中监测每搏量或心输出量?(4)可以监测哪些区域和微循环标志物,以及如何在休克中评估细胞功能?(5)使用血流动力学监测指导休克治疗的证据是什么?使用了四种类型的声明:定义、推荐、最佳实践和事实陈述。
共制定了44项声明。主要的新声明包括:(1)关于个体化血压目标的声明;(2)关于液体反应性评估和预测的声明;(3)关于使用超声心动图和血流动力学监测的声明。
本共识提供了44项声明,可用于床边对休克患者进行诊断、治疗和监测。