槐花中的新麦芽醇苷。

New maltol glycosides from Flos Sophorae.

作者信息

Zhang Yi, Qu Lu, Liu Lili, Li Xiaoxia, Liu Erwei, Han Lifeng, Fang Shiming, Gao Xiumei, Wang Tao

机构信息

Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin, 300193, China.

出版信息

J Nat Med. 2015 Apr;69(2):249-54. doi: 10.1007/s11418-014-0877-1. Epub 2014 Nov 15.

DOI:10.1007/s11418-014-0877-1

PMID:25398298

Abstract

Three new maltol glycosides, designated soyamalosides A (1), B (2), and C (3), together with eight known compounds (4-11), were obtained from a 70 % EtOH extract of Flos Sophorae. Their structures were elucidated by chemical and spectroscopic methods. Of the known compounds, this is the first report of 4-6, 9, and 11 in the Sophora genus. Compounds 2, 3, and 10 showed significant protective effects against antimycin A-induced L6 cell injury.

摘要

从槐花70%乙醇提取物中获得了三种新的麦芽醇糖苷，分别命名为大豆麦芽苷A（1）、B（2）和C（3），以及八个已知化合物（4 - 11）。通过化学和光谱方法阐明了它们的结构。在已知化合物中，这是槐属植物中4 - 6、9和11的首次报道。化合物2、3和10对抗霉素A诱导的L6细胞损伤显示出显著的保护作用。