Gabuniia R I, Godin V P, Gritsaĭ A A, Kirsanov A G, Aplevich N N
Med Radiol (Mosk). 1989 Apr;34(4):49-53.
A scintigraphic picture was observed in 51 patients suffering from breast cancer with metastatic involvement of the skeleton (polychemotherapy + radiotherapy of pelvic bones and lumbar spine + hormonotherapy) to determine the role of scintigraphy in the assessment of therapeutic effectiveness. According to scintigraphic signs of changes in RP accumulation in metastases the following groups were singled out: a complete effect, a partial effect, stabilization, progression of disease. The mean interval from the onset of therapy up to the appearance of scintigraphic signs of a therapeutic effect was 8.6 mos. A high degree of correlation between scintigraphic signs of a therapeutic effect and the time course of the pain syndrome in the skeletal bones was shown.