Temiz Mustafa Zafer, Yuruk Emrah, Teberik Kutlu, Akbas Burcu Kadriye, Piroglu Mustafa Devrim, Oztorun Hande Selvi, Kandirali Engin
Department of Urology, Bitlis State Hospital, Besminare Mh. 13000, Besminare/BITLIS, Turkey.
Department of Urology, Bagcilar Training and Research Hospital, Merkez Mahallesi Mimar Sinan Caddesi 6. Sokak, Bagcilar/Istanbul, Turkey.
Int J Surg Case Rep. 2014;5(12):1258-60. doi: 10.1016/j.ijscr.2014.10.087. Epub 2014 Nov 20.
Ischemic hepatitis (IH) is the necrosis of the centrilobular hepatocytes of liver and is secondary to liver hypoperfusion in most of the cases. The diagnosis is usually based on biochemical findings due to the absence of symptoms and signs. Although the disease course is often mild, and sometimes is even not diagnosed, the outcome is poor if the etiology of hypotension and liver anoxia is not promptly corrected.
A 64-year-old patient who underwent percutaneous nephrolithotomy (PNL) for right renal pelvic stone developed acute IH at first postoperative day as a result of hemorrhage related severe hypotension. After restoring hemodynamic parameters, she completely recovered 2 weeks after the operation.
IH is a frequent cause of marked serum aminotransferase elevation and most commonly occurs as a result of arterial hypoxemia and insufficient hepatic perfusion. Although no specific treatment of IH exists, stabilizing the hemodynamic parameters of the patient resolves the problem in most of the cases.
This case is presented to demonstrate that ischemic hepatitis should be kept in mind if severe hemorrhage occurs during PNL.
缺血性肝炎(IH)是肝小叶中心肝细胞的坏死,大多数情况下继发于肝脏灌注不足。由于缺乏症状和体征,诊断通常基于生化检查结果。尽管该病病程通常较轻,有时甚至未被诊断出来,但如果低血压和肝脏缺氧的病因未得到及时纠正,预后较差。
一名64岁患者因右肾盂结石接受经皮肾镜取石术(PNL),术后第一天因出血相关的严重低血压而发生急性缺血性肝炎。恢复血流动力学参数后,她在术后2周完全康复。
缺血性肝炎是血清氨基转移酶显著升高的常见原因,最常见于动脉血氧不足和肝脏灌注不足。尽管目前尚无针对缺血性肝炎的特异性治疗方法,但在大多数情况下,稳定患者的血流动力学参数可解决问题。
本病例旨在表明,经皮肾镜取石术期间发生严重出血时应考虑缺血性肝炎。