Dua Anahita, Furlough Courtney L, Ray Hunter, Sharma Sneha, Upchurch Gilbert R, Desai Sapan S
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisc.
Department of Surgery, University of Texas Medical School at Houston, Houston, Tex.
J Vasc Surg. 2014 Dec;60(6):1446-51. doi: 10.1016/j.jvs.2014.08.111. Epub 2014 Oct 14.
Patient factors that contribute to mortality from abdominal aortic aneurysm (AAA) repair have been previously described, but few studies have delineated the hospital factors that may be associated with an increase in patient mortality after AAA. This study used a large national database to identify hospital factors that affect mortality rates after open repair (OAR) and endovascular AAA repair (EVAR) of elective and ruptured AAA.
A retrospective analysis was completed using the Nationwide Inpatient Sample from 1998 to 2011. International Classification of Disease, Ninth Revision codes were used to identify patients who underwent elective or ruptured AAA repair by OAR or EVAR. The association between mortality and hospital covariates, including ownership, bed size, region, and individual hospital volume for these patients was statistically delineated by analysis of variance, χ(2), and Mann-Kendall trend analysis.
A total of 128,232 patients were identified over the 14-year period, of which 88.5% were elective procedures and 11.5% were performed acutely for rupture. Most hospitals that complete elective OAR do between one and 50 cases, with mortality between 0% and 40%. Hospitals with mortality >40% uniformly complete fewer than five elective OAR cases annually and fall in the bottom 2.5% of all hospitals for mortality. Most hospitals that complete elective EVAR do between one and 70 cases, with mortality between 0% and 13%. Hospitals with mortality >13% uniformly complete fewer than eight elective EVAR cases annually and fall in the bottom 2.5% of all hospitals for mortality. The majority of hospitals that complete OAR or EVAR for ruptured AAA have between 0% to 100% for mortality, indicative of the high mortality risk associated with rupture.
Hospitals that complete fewer than five OARs or eight EVARs annually have significantly greater mortality compared with their counterparts. Improved implementation of best practices, more detailed informed consent to include hospital mortality data, and better regional access to health care may improve survival after elective AAA repair.
先前已描述过导致腹主动脉瘤(AAA)修复术后死亡的患者因素,但很少有研究阐明可能与AAA患者术后死亡率增加相关的医院因素。本研究使用一个大型国家数据库来确定影响择期和破裂性AAA开放修复(OAR)及血管内AAA修复(EVAR)术后死亡率的医院因素。
使用1998年至2011年的全国住院患者样本完成回顾性分析。使用国际疾病分类第九版编码来识别接受OAR或EVAR进行择期或破裂性AAA修复的患者。通过方差分析、χ²检验和曼-肯德尔趋势分析,对这些患者的死亡率与医院协变量(包括所有权、床位规模、地区和各医院的手术量)之间的关联进行统计学描述。
在这14年期间共识别出128,232例患者,其中88.5%为择期手术,11.5%为因破裂而急诊进行的手术。大多数完成择期OAR的医院每年进行1至50例手术,死亡率在0%至40%之间。死亡率>40%的医院每年完成的择期OAR病例均少于5例,且死亡率处于所有医院的后2.5%。大多数完成择期EVAR的医院每年进行1至70例手术,死亡率在0%至13%之间。死亡率>13%的医院每年完成的择期EVAR病例均少于8例,且死亡率处于所有医院的后2.5%。大多数为破裂性AAA完成OAR或EVAR的医院死亡率在0%至100%之间,这表明与破裂相关的高死亡风险。
与同行相比,每年完成少于5例OAR或8例EVAR的医院死亡率显著更高。更好地实施最佳实践、更详细的知情同意(包括医院死亡率数据)以及更好的区域医疗服务可改善择期AAA修复后的生存率。