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低位直肠癌患者行括约肌间直肠切除术后盆腔脓毒症风险低。

Low risk of pelvic sepsis after intersphincteric proctectomy in patients with low rectal cancer.

作者信息

Eriksen Marianne H, Maina Pierre, Jensen Kenneth Højsgaard

机构信息

Kirurgisk Gastroenterologisk Afdeling D, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark.

出版信息

Dan Med J. 2014 Dec;61(12):A4972.

Abstract

INTRODUCTION

Pelvic sepsis after Hartmann's procedure for low rectal cancer is a frequent complication. It has been reported at a frequency of 12.2-17.2% and has even reached 33% when the transection level of the rectum is ≤ 2 cm from the anal verge. The aim of this study was to examine whether intersphincteric proctectomy reduces the frequency of pelvic sepsis in patients operated with an extended Hartmann's procedure for rectal cancer.

METHODS

Patients undergoing elective extended Hartmann's procedure with an intersphincteric proctectomy from 2010 until 2014 were reviewed retrospectively. Patient characteristics and post-operative complications were obtained and analysed.

RESULTS

A total of 50 patients were included in this analysis. Sixteen were female, the median age was 73 years, and the median BMI was 26 kg/m2. Furthermore, the American Society of Anesthesiologists (ASA) scores were as follows: ASA 1 (28%), ASA 2 (60%), and ASA 3 (12%); their tumour-node-metastasis (TNM) staging was TNM: ≤ T2 (30%), T3 (50%), and T4 (20%); and 26% had received neoadjuvant radiotherapy, whereas 40% had received chemotherapy. A total of three patients (6%) developed a post-operative pelvic sepsis. The median length of post-operative hospitalisation was 9.5 days. Overall mortality was 4% (n = 50). The most frequent surgical complication to intersphincteric proctectomy was perineal wound infection, occurring in 20%.

DISCUSSION

This study suggests a reduction in the frequency of pelvic sepsis when intersphincteric proctectomy is performed in patients who undergo extended Hartmann's procedure. The frequency is, however, larger than that reported herein when the rectal stump is left long. Intersphincteric proctectomy should therefore primarily be reserved for low cancers with short rectal stumps.

FUNDING

not relevant.

TRIAL REGISTRATION

not relevant.

摘要

引言

低位直肠癌Hartmann手术术后盆腔感染是一种常见并发症。据报道,其发生率为12.2%-17.2%,当直肠切断平面距肛缘≤2cm时,发生率甚至可达33%。本研究的目的是探讨括约肌间直肠切除术是否能降低行扩大Hartmann手术治疗直肠癌患者的盆腔感染发生率。

方法

回顾性分析2010年至2014年接受选择性扩大Hartmann手术并行括约肌间直肠切除术的患者。获取并分析患者特征及术后并发症。

结果

本分析共纳入50例患者。其中女性16例,中位年龄73岁,中位体重指数为26kg/m²。此外,美国麻醉医师协会(ASA)评分如下:ASA 1级(28%),ASA 2级(60%),ASA 3级(12%);肿瘤-淋巴结-转移(TNM)分期为:TNM≤T2(30%),T3(50%),T4(20%);26%的患者接受了新辅助放疗,40%的患者接受了化疗。共有3例患者(6%)发生术后盆腔感染。术后住院时间中位数为9.5天。总死亡率为4%(n = 50)。括约肌间直肠切除术最常见的手术并发症是会阴伤口感染,发生率为20%。

讨论

本研究表明,行扩大Hartmann手术的患者实施括约肌间直肠切除术后盆腔感染发生率降低。然而,当直肠残端留得较长时,感染发生率高于本文报道。因此,括约肌间直肠切除术应主要用于直肠残端较短的低位癌。

资金支持

无关。

试验注册

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