Kim Young Il, Kang Hyo Cheol, Lee Ho Sung, Choi Jae Sung, Seo Ki Hyun, Kim Yong Hoon, Na Juock
University of Soonchunhyang College of Medicine, University Hospital for Pulmonary Diseases, Cheonan, Republic of Korea.
University of Soonchunhyang College of Medicine, University Hospital for Pulmonary Diseases, Cheonan, Republic of Korea.
Ann Thorac Surg. 2014 Nov;98(5):1832-5. doi: 10.1016/j.athoracsur.2013.12.051. Epub 2014 Oct 30.
Pulmonary mucormycosis is a rare opportunistic invasive fungal infection involving the pulmonary vasculature in immunocompromised patients. Pseudoaneurysm of pulmonary artery in mucormycosis is a rare fatal complication after invasion and rupture of a pulmonary artery. We report a patient with diabetes mellitus and incidental lung cancer who developed massive hemoptysis because of a huge pseudoaneurysm of the left pulmonary artery by mucormycosis. Although the patient had been managed by amphotericin B followed by left pneumonectomy for persistent hemoptysis, he died from septic shock and multiorgan failure after surgery. Histologic analysis of a surgical specimen revealed concomitant squamous cell lung cancer.
肺毛霉病是一种罕见的机会性侵袭性真菌感染,累及免疫功能低下患者的肺血管。毛霉病所致肺动脉假性动脉瘤是肺动脉受侵袭破裂后罕见的致命并发症。我们报告1例糖尿病合并偶发性肺癌患者,因毛霉病导致左肺动脉巨大假性动脉瘤而发生大量咯血。尽管患者接受了两性霉素B治疗,随后因持续性咯血行左肺切除术,但术后死于感染性休克和多器官功能衰竭。手术标本的组织学分析显示合并鳞状细胞肺癌。