梅毒与人类免疫缺陷病毒感染：男男性行为者中的一种地方性感染
[Syphilis and human immunodeficiency virus infection: an endemic infection in men who have sex with men].
作者信息
González-Domenech Carmen M, Antequera Martín-Portugués Isabel, Clavijo-Frutos Encarnación, Márquez-Solero Manuel, Santos-González Jesús, Palacios-Muñoz Rosario
机构信息
Unidad de Gestión Clínica de Enfermedades Infecciosas y Microbiología Clínica, Hospital Virgen de la Victoria, Málaga, España.
Unidad de Gestión Clínica de Medicina Interna, Hospital Virgen de la Victoria, Málaga, España.
出版信息
Enferm Infecc Microbiol Clin. 2015 Jan;33(1):32-6. doi: 10.1016/j.eimc.2014.07.013. Epub 2014 Oct 22.
OBJECTIVE
to analyse epidemiological, clinical, and analytical features of HIV-infected men who have sex with men (MSM) diagnosed with syphilis in the Infectious Diseases Unit (Hospital Virgen de la Victoria, Málaga, Spain) during 2004-2013.
PATIENTS AND METHODS
An observational study was conducted on 196 syphilis episodes in 167 MSM infected with HIV (2004-2013). Epidemiological, clinical, and analytical data were collected. Annual syphilis incidence among HIV-MSM is calculated as the number of syphilis episodes among MSM in one year divided by the number of MSM followed up in that year.
RESULTS
Incidence ranged from 1.2% (2007) to 7.8% (2012). There were asymptomatic episodes in 42.8% cases, and an HIV-syphilis coincident diagnosis in 28.5%.
CONCLUSIONS
The annual incidence of syphilis has increased within HIV infected MSM. One third of the syphilis episodes were simultaneous to HIV diagnosis and near half of them were asymptomatic.
目的
分析2004年至2013年期间在西班牙马拉加市维多利亚圣母医院传染病科诊断为梅毒的男男性行为者（MSM）感染艾滋病毒的流行病学、临床和分析特征。
患者与方法
对167名感染艾滋病毒的男男性行为者（2004年至2013年）中的196例梅毒发作进行了一项观察性研究。收集了流行病学、临床和分析数据。艾滋病毒感染男男性行为者的年度梅毒发病率计算为一年内男男性行为者中的梅毒发作次数除以该年随访的男男性行为者人数。
结果
发病率从1.2%（2007年）到7.8%（2012年）不等。42.8%的病例有无症状发作，28.5%的病例艾滋病毒与梅毒同时诊断。
结论
感染艾滋病毒的男男性行为者中梅毒的年发病率有所增加。三分之一的梅毒发作与艾滋病毒诊断同时发生，近一半为无症状发作。
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