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重复经颅磁刺激治疗成瘾行为:对疗效、技术和方法学考虑因素的批判性文献综述。

The use of repetitive transcranial magnetic stimulation for modulating craving and addictive behaviours: a critical literature review of efficacy, technical and methodological considerations.

出版信息

Neurosci Biobehav Rev. 2014 Nov;47:592-613. doi: 10.1016/j.neubiorev.2014.10.013.

Abstract

OBJECTIVES

Repetitive transcranial magnetic stimulation (rTMS) is a potential therapeutic intervention for the treatment of addiction. This critical review aims to summarise the recent developments with respect to the efficacy of rTMS for all types of addiction and related disorders (including eating disorders), and concentrates on the associated methodological and technical issues.

METHODS

The bibliographic search consisted of a computerised screening of the Medline and ScienceDirect databases up to December 2013. Criteria for inclusion were the target problem was an addiction, a related disorder, or craving; the intervention was performed using rTMS; and the study was a clinical trial.

RESULTS

Of the potential 638 articles, 18 met the criteria for inclusion. Most of these (11 of the 18) supported the efficacy of rTMS, especially in the short term. In most cases, the main assessment criterion was the measurement of craving using a Visual Analogue Scale.

DISCUSSION

The results are discussed with respect to the study limitations and, in particular, the many methodological and technical discrepancies that were identified. Key recommendations are provided.

摘要

目的

重复经颅磁刺激(rTMS)是一种有潜力的成瘾治疗干预手段。本综述旨在总结 rTMS 治疗所有类型成瘾及相关障碍(包括饮食障碍)的最新进展,并重点关注相关的方法学和技术问题。

方法

文献检索包括对 Medline 和 ScienceDirect 数据库进行计算机筛选,检索截至 2013 年 12 月。纳入标准为:目标问题为成瘾、相关障碍或渴求;干预措施使用 rTMS;研究为临床试验。

结果

在潜在的 638 篇文章中,有 18 篇符合纳入标准。其中大多数(18 篇中的 11 篇)支持 rTMS 的疗效,尤其是在短期治疗中。在大多数情况下,主要评估标准是使用视觉模拟量表测量渴求。

讨论

结果讨论了研究的局限性,特别是确定的许多方法学和技术差异。提供了关键建议。

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