Azouz Hanan Galal, Kozou Hesham, Khalil Mona, Abdou Rania M, Sakr Mohamed
Department of Pediatrics, Faculty of Medicine, Alexandria University, Egypt.
Audiology Unit, Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Egypt.
Int J Pediatr Otorhinolaryngol. 2014 Dec;78(12):2297-300. doi: 10.1016/j.ijporl.2014.10.039. Epub 2014 Nov 4.
To study the auditory profile at different levels of the auditory system in children with ASD and to verify the role of (Central) auditory processing disorder as an essential pathology of the autistic disorder or as an associated co-morbidity, and to establish the correlation between CAP findings and the language delay in these cases.
The study included 30 children with definite autistic disorder according to DSM-IV-TR criteria and ADI-R among those attending the outpatient neuropsychiatry clinic of Alexandria University Children Hospital at El Shatby. An informed consent was taken from all patients in this part of the study. Confidentiality of the records was maintained.
All cases were subjected to complete history taking and examination; special assessment to language skills and evoked potentials were done.
The results concluded that (central) auditory processing disorder is an essential pathology of the autistic disorder. Autistic children possess a dysfunctioning or an immature central auditory nervous system at both the brainstem and cortical levels.
研究自闭症谱系障碍(ASD)儿童听觉系统不同水平的听觉特征,验证(中枢)听觉处理障碍作为自闭症障碍的本质病理或相关共病的作用,并确定这些病例中听觉处理评估(CAP)结果与语言发育迟缓之间的相关性。
本研究纳入了亚历山大大学儿童医院埃尔沙特比门诊神经精神病科中符合DSM-IV-TR标准及孤独症诊断访谈量表修订版(ADI-R)的30名确诊为自闭症障碍的儿童。本研究这一部分的所有患者均签署了知情同意书。记录保持保密。
所有病例均进行了完整的病史采集和检查;对语言技能和诱发电位进行了专项评估。
结果表明,(中枢)听觉处理障碍是自闭症障碍的本质病理。自闭症儿童在脑干和皮层水平均存在中枢听觉神经系统功能障碍或发育不成熟的情况。