Rothe Thomas
Abteilung Innere Medizin, Zürcher Höhenklinik Davos, Davos Clavadel.
Praxis (Bern 1994). 2014 Dec 10;103(25):1509-14. doi: 10.1024/1661-8157/a001866.
COPD is not a homogenous disease but consists of at least four different phenotypes: Emphysema, COPD with chronic bronchitis, asthma-COPD overlap syndrome (ACOS), and COPD with recurrent exacerbations. With differentiation, treatment can be designed phenotype-specific. Some modern drugs are not indicated in all phenotypes.
慢性阻塞性肺疾病并非一种同质化疾病,而是至少由四种不同的表型组成:肺气肿型、慢性支气管炎型慢性阻塞性肺疾病、哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)以及反复加重型慢性阻塞性肺疾病。通过区分表型,可以制定针对性的治疗方案。一些现代药物并非适用于所有表型。